腺病毒六邻体单克隆抗体，具有群特异性，有可能用作诊断试剂。
Adenovirus hexon monoclonal antibody that is group specific and potentially useful as a diagnostic reagent.
作者信息
Cepko C L, Whetstone C A, Sharp P A
出版信息
J Clin Microbiol. 1983 Feb;17(2):360-4. doi: 10.1128/jcm.17.2.360-364.1983.
Abstract
A monoclonal antibody to the adenovirus 2 hexon protein was produced and characterized as a group-specific antibody. Positive reactivity in immunoprecipitation, indirect immunofluorescence, and radioimmunoassays was observed with human, canine, swine, bovine, murine, and simian adenoviruses. This monoclonal antibody should provide a specific and sensitive diagnostic reagent for detection of all mammalian adenoviruses.
摘要
制备了一种针对腺病毒2型六邻体蛋白的单克隆抗体，并将其鉴定为一种群特异性抗体。在免疫沉淀、间接免疫荧光和放射免疫分析中观察到该抗体与人、犬、猪、牛、鼠和猴腺病毒有阳性反应。这种单克隆抗体应为检测所有哺乳动物腺病毒提供一种特异性和灵敏的诊断试剂。
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