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腺病毒六邻体单克隆抗体，具有群特异性，有可能用作诊断试剂。

Adenovirus hexon monoclonal antibody that is group specific and potentially useful as a diagnostic reagent.

作者信息

Cepko C L, Whetstone C A, Sharp P A

出版信息

J Clin Microbiol. 1983 Feb;17(2):360-4. doi: 10.1128/jcm.17.2.360-364.1983.

DOI:10.1128/jcm.17.2.360-364.1983
PMID:6339552
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC272638/
Abstract

A monoclonal antibody to the adenovirus 2 hexon protein was produced and characterized as a group-specific antibody. Positive reactivity in immunoprecipitation, indirect immunofluorescence, and radioimmunoassays was observed with human, canine, swine, bovine, murine, and simian adenoviruses. This monoclonal antibody should provide a specific and sensitive diagnostic reagent for detection of all mammalian adenoviruses.

摘要

制备了一种针对腺病毒2型六邻体蛋白的单克隆抗体，并将其鉴定为一种群特异性抗体。在免疫沉淀、间接免疫荧光和放射免疫分析中观察到该抗体与人、犬、猪、牛、鼠和猴腺病毒有阳性反应。这种单克隆抗体应为检测所有哺乳动物腺病毒提供一种特异性和灵敏的诊断试剂。

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1
Adenovirus hexon monoclonal antibody that is group specific and potentially useful as a diagnostic reagent.腺病毒六邻体单克隆抗体，具有群特异性，有可能用作诊断试剂。
J Clin Microbiol. 1983 Feb;17(2):360-4. doi: 10.1128/jcm.17.2.360-364.1983.
2
Characterization of a series of monoclonal antibodies specific for bovine adenovirus serotype BAV3 hexon antigen and their use in an ELISA for detection of adenoviral hexons.一系列针对牛腺病毒血清型BAV3六邻体抗原的单克隆抗体的特性及其在腺病毒六邻体检测酶联免疫吸附测定中的应用。
Acta Microbiol Hung. 1990;37(3):307-14.
3
The composed antigenic structure of the adenovirus hexon protein.腺病毒六邻体蛋白的复合抗原结构。
Virologie. 1988 Oct-Dec;39(4):267-80.
4
[Detection of antibodies to adenovirus hexon in the sera of nonimmunized rabbits].[未免疫兔血清中腺病毒六邻体抗体的检测]
Mikrobiol Zh (1978). 1982;44(6):91-2.
5
Antibody to the type 5 adenovirus hexon polypeptide: detection of nascent polypeptides in the cytoplasm of infected KB cells.抗5型腺病毒六邻体多肽抗体：检测受感染KB细胞胞质中的新生多肽。
Intervirology. 1974;4(4):226-36. doi: 10.1159/000149967.
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[Antibodies to hexon in the immunological inactivation of adenoviruses].[腺病毒免疫灭活中六邻体抗体的作用]
Mikrobiol Zh (1978). 1981 Mar-Apr;43(2):212-8.
7
Antigenic determinants of adenovirus capsids. I. Measurement of antibody cross-reactivity.腺病毒衣壳的抗原决定簇。I. 抗体交叉反应性的测定。
J Immunol. 1976 Jan;116(1):19-24.
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[Antigenic determinants of the hexon of bovine adenovirus type 3].[牛腺病毒3型六邻体的抗原决定簇]
Vopr Virusol. 1986 Sep-Oct;31(5):620-3.
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Application of a solid-phase immunofluorometric assay to the selection of monoclonal antibody specific for the adenovirus group-reactive hexon antigen.固相免疫荧光测定法在选择针对腺病毒群反应性六邻体抗原的单克隆抗体中的应用。
Arch Virol. 1984;80(1):1-10. doi: 10.1007/BF01315289.
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[The antigenic relationship of human and bovine adenoviruses studied by the fluorescent antibody method].[用荧光抗体法研究人腺病毒与牛腺病毒的抗原关系]
Mikrobiol Zh (1978). 1986 May-Jun;48(3):67-70.

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Architecture of the Adenovirus Capsid.腺病毒衣壳的结构
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CHARACTERIZATION OF AGENTS ISOLATED FROM MARKET CHICKENS IN A QUEST FOR ENTERIC VIRUSES.从市售鸡中分离的病原体的特性鉴定，以寻找肠道病毒
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THE PREPARATION OF I-131-LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC RADIOACTIVITY.高比放射性碘-131标记人生长激素的制备
缬更昔洛韦可抑制免疫功能低下的雌性和雄性叙利亚仓鼠体内人腺病毒的复制及病变。
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A protein multiplex microarray substrate with high sensitivity and specificity.一种具有高灵敏度和特异性的蛋白质多重微阵列底物。
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Comparison of a monoclonal antibody with a polyclonal serum in an enzyme-linked immunosorbent assay for detecting adenovirus.在用于检测腺病毒的酶联免疫吸附测定中，单克隆抗体与多克隆血清的比较。
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Use of the biotin-avidin system to study the specificity of antibodies against respiratory syncytial virus.利用生物素-抗生物素蛋白系统研究抗呼吸道合胞病毒抗体的特异性。
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Aberrant distribution of human adenovirus type 2 late proteins in monkey kidney cells.人腺病毒2型晚期蛋白在猴肾细胞中的异常分布。
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Immunoprecipitation with two-dimensional pools as a hybridoma screening technique: production and characterization of monoclonal antibodies against adenovirus 2 proteins.以二维文库进行免疫沉淀作为一种杂交瘤筛选技术：抗腺病毒2型蛋白单克隆抗体的制备与鉴定
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The evolution of the adenoviral genome.腺病毒基因组的进化
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The adenovirus hexon protein. The primary structure of the polypeptide and its correlation with the hexon gene.腺病毒六邻体蛋白。多肽的一级结构及其与六邻体基因的相关性。
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Cleavage of structural proteins during the assembly of the head of bacteriophage T4.在噬菌体T4头部组装过程中结构蛋白的切割
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The structural and functional diversity of Adenovirus capsid components.腺病毒衣壳成分的结构和功能多样性。
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A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels.一种用于检测聚丙烯酰胺凝胶中氚标记蛋白质和核酸的胶片检测方法。
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