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回肠造口术婴幼儿的钠需求

Sodium needs of infants and children with ileostomy.

作者信息

Schwarz K B, Ternberg J L, Bell M J, Keating J P

出版信息

J Pediatr. 1983 Apr;102(4):509-13. doi: 10.1016/s0022-3476(83)80175-9.

Abstract

We studied gastrointestinal tract excretion of sodium and water in seven infants with an abdominal ileostomy (group 1) and three children with a Soave ileoendorectal pull-through (group 2). When the daily sodium intake of the patients was 5 to 7 mEq/kg (twice usual maintenance), average daily ileal sodium losses were 2.4 mEq/kg body weight in group 1 and 3.3 mEq/kg in group 2. Ten days after ileostomy closure in group 1, when the infants' daily sodium intake averaged 2 to 3 mEq/kg/day, gastrointestinal tract sodium losses were reduced to 0.3 mEq/kg body weight/day. The mean daily fecal weight and water also decreased after closure. Mean serum aldosterone concentration before closure was 84 ng/ml, and declined to 58 ng/100 ml after closure; and mean plasma renin values fell from 8.8 to 2.9 ng/ml/hr. In the children with an ileoendorectal pull-through, daily sodium intake was restricted to 0.3 to 0.5 mEq/kg/day, an amount that would maintain balance in a child of similar age with normal sodium conservation. Mean serum aldosterone concentration increased to 501 ng/ml (normal 1 to 22.7). Although renal conservation of sodium occurred promptly, gastrointestinal losses of sodium and water continued and the patients' sodium balance became negative. The diet of a patient with an ileostomy should include increased amounts of sodium until bowel continuity is restored.

摘要

我们研究了7例患有腹部回肠造口术的婴儿(第1组)和3例接受Soave经肛门直肠拖出术的儿童(第2组)胃肠道对钠和水的排泄情况。当患者的每日钠摄入量为5至7 mEq/kg(通常维持量的两倍)时,第1组回肠每日钠丢失量平均为2.4 mEq/kg体重,第2组为3.3 mEq/kg。第1组回肠造口关闭10天后,婴儿的每日钠摄入量平均为2至3 mEq/kg/天,胃肠道钠丢失量降至0.3 mEq/kg体重/天。关闭后,平均每日粪便重量和水分也有所减少。关闭前平均血清醛固酮浓度为84 ng/ml,关闭后降至58 ng/100 ml;平均血浆肾素值从8.8降至2.9 ng/ml/hr。在接受经肛门直肠拖出术的儿童中,每日钠摄入量限制在0.3至0.5 mEq/kg/天,这一量可使年龄相仿、钠保留正常的儿童维持平衡。平均血清醛固酮浓度升至501 ng/ml(正常范围为1至22.7)。尽管肾脏对钠的保留迅速发生,但胃肠道对钠和水的丢失仍在继续,患者的钠平衡变为负值。回肠造口患者的饮食应增加钠的摄入量,直至肠道连续性恢复。

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