Battaglia A, Adamo M
Minerva Med. 1983 Mar 10;74(9-10):493-8.
32 patients (13 women and 19 men) with slight to severe hypertension were treated during an open medium term study with acebutolol, a beta-antagonist which is cardioselective and at the same time has an intrinsic sympatheticomimetic effect. The average daily dose of the drug was 743 mg. In about 69% of the cases results were excellent or good, in 21% fair and in the remaining 9% no improvement was observed. Average cardiac frequency was 93 beats per minute before treatment started and about 90 days later this had fallen to 70.6 beats per minute. Almost no side effects were observed.
在一项开放性中期研究中，对32例（13名女性和19名男性）轻度至重度高血压患者使用醋丁洛尔进行治疗。醋丁洛尔是一种β受体阻滞剂，具有心脏选择性，同时还具有内在拟交感神经活性。该药物的平均日剂量为743毫克。在约69%的病例中，治疗效果为优或良；21%为中等；其余9%未见改善。治疗开始前平均心率为每分钟93次，约90天后降至每分钟70.6次。几乎未观察到副作用。
