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从大鼠体内回收的曼氏血吸虫皮层对宿主蛋白质的获取。

Acquisition of host proteins by the tegument of Schistosoma mansoni recovered from rats.

作者信息

Yong W K, Das P K

出版信息

Z Parasitenkd. 1983;69(1):53-60. doi: 10.1007/BF00934010.

DOI:10.1007/BF00934010
PMID:6340359
Abstract

Four-week-old Schistosoma mansoni collected from experimentally infected albino rats were shown by a fluorescent antibody technique to possess several serum proteins of host origin, including IgM, IgG, complement and red blood cell components. The capacity of these rat-derived worms to acquire and shed host proteins was also demonstrated in vitro with fluoresceinated antibody-labelled worms in the presence of xenogeneic molecules. The implications of these results are discussed in relation to the mechanisms of parasite evasion and "self-cure" phenomenon.

摘要

通过荧光抗体技术显示,从实验感染的白化大鼠体内收集的四周龄曼氏血吸虫含有几种宿主来源的血清蛋白,包括IgM、IgG、补体和红细胞成分。在异种分子存在的情况下,用荧光素标记抗体标记的蠕虫在体外也证明了这些源自大鼠的蠕虫获取和释放宿主蛋白的能力。结合寄生虫逃避机制和“自愈”现象讨论了这些结果的意义。

相似文献

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Acquisition of host proteins by the tegument of Schistosoma mansoni recovered from rats.从大鼠体内回收的曼氏血吸虫皮层对宿主蛋白质的获取。
Z Parasitenkd. 1983;69(1):53-60. doi: 10.1007/BF00934010.
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本文引用的文献

1
A comparison of common laboratory animals as experimental hosts for Schistosoma mansoni.作为曼氏血吸虫实验宿主的常见实验动物比较。
J Parasitol. 1949 Apr;35(2):156-70.
2
The relative susceptibilities of the commonly-used laboratory mammal to infection by Schistosoma mansoni.常用实验哺乳动物对曼氏血吸虫感染的相对易感性。
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3
RESISTANCE INDUCED IN RATS BY PREVIOUS EXPOSURE TO AND BY VACCINATION WITH FRESH HOMOGENATES OF SCHISTOSOMA MANSONI.先前接触曼氏血吸虫新鲜匀浆及接种该匀浆后在大鼠体内诱导产生的抵抗力
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THE BIOLOGY OF SCHISTOSOMA MANSONI IN LABORATORY RATS.曼氏血吸虫在实验大鼠中的生物学特性
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5
Studies of the antibody-dependent killing of schistosomula of Schistosoma mansoni employing haptenic target antigens. I. Evidence that the loss in susceptibility to immune damage undergone by developing schistosomula involves a change unrelated to the masking of parasite antigens by host molecules.利用半抗原靶抗原对曼氏血吸虫童虫进行抗体依赖性杀伤的研究。I. 发育中童虫对免疫损伤易感性降低的证据表明,这涉及到一种与宿主分子掩盖寄生虫抗原无关的变化。
J Exp Med. 1980 Jul 1;152(1):41-53. doi: 10.1084/jem.152.1.41.
6
Tegument-associated antigen modulation by adult male Schistosoma mansoni.成年雄性曼氏血吸虫对皮层相关抗原的调节作用
J Immunol. 1980 Feb;124(2):806-11.
7
Immune evasion by Schistosoma mansoni: loss of susceptibility to antibody or complement-dependent eosinophil attack by schistosomula cultured in medium free of macromolecules.曼氏血吸虫的免疫逃避:在无大分子培养基中培养的童虫对抗体或补体依赖的嗜酸性粒细胞攻击的易感性丧失。
Parasitology. 1981 Jun;82(Pt 3):357-74. doi: 10.1017/s0031182000066890.
8
Acquired resistance to experimental infections of Schistosoma mansoni in the albino rat.白化大鼠对曼氏血吸虫实验性感染的获得性抗性
Parasitology. 1965 Nov;55(4):711-7.
9
Schistosoma mansoni: immunity in Macaca mulatta.曼氏血吸虫:恒河猴的免疫
Exp Parasitol. 1971 Jun;29(3):463-79. doi: 10.1016/0014-4894(71)90056-7.
10
Resistance to experimental infection with Schistosoma mansoni in rhesus monkeys induced by the transfer of adult worms.
Trans R Soc Trop Med Hyg. 1967;61(4):517-33. doi: 10.1016/0035-9203(67)90102-2.