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Clinical pharmacokinetics of metronidazole.

作者信息

Ralph E D

出版信息

Clin Pharmacokinet. 1983 Jan-Feb;8(1):43-62. doi: 10.2165/00003088-198308010-00003.

DOI:10.2165/00003088-198308010-00003
PMID:6340904
Abstract
摘要

相似文献

1
Clinical pharmacokinetics of metronidazole.甲硝唑的临床药代动力学
Clin Pharmacokinet. 1983 Jan-Feb;8(1):43-62. doi: 10.2165/00003088-198308010-00003.
2
The fate of metronidazole and tis implications in chemotherapy.
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3
Pharmacokinetics and bioavailability of metronidazole after tablets, suppositories and intravenous administration.甲硝唑片剂、栓剂及静脉给药后的药代动力学和生物利用度。
Scand J Gastroenterol Suppl. 1984;91:45-60.
4
Comparison of the pharmacokinetics of metronidazole in healthy female volunteers following either a single oral or intravenous dose.健康女性志愿者单次口服或静脉注射甲硝唑后的药代动力学比较。
Br J Clin Pharmacol. 1979 Oct;8(4):337-41. doi: 10.1111/j.1365-2125.1979.tb04715.x.
5
[Radiosensitization with metronidazole. Pharmacocinetical comparison by means of blood level curves after administration of "metronidazol" in the form of tablets, suppositories, and enemas (author's transl)].甲硝唑的放射增敏作用。通过口服片剂、栓剂和灌肠剂形式的“甲硝唑”后血药浓度曲线进行的药代动力学比较(作者译)
Strahlentherapie. 1979 Dec;155(12):811-6.
6
Pharmacokinetics of metronidazole in healthy adult volunteers after tablets and suppositories.
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7
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Disposition and metabolism of metronidazole in patients with liver failure.
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The pharmacokinetics of oral and intravenous metronidazole in man.
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[Prevention of postoperative anaerobic infections. Economic significance of metronidazole suppositories].
Presse Med. 1984 Jan 28;13(3):141-4.

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Clinical pharmacokinetics of metronidazole: a systematic review and meta-analysis.甲硝唑的临床药代动力学:一项系统评价与荟萃分析。
Antimicrob Agents Chemother. 2025 Sep 3;69(9):e0190424. doi: 10.1128/aac.01904-24. Epub 2025 Jul 31.
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Cost-Effective Nanosensor Solutions for Ultra-Sensitive Detection of Metronidazole.用于超灵敏检测甲硝唑的经济高效纳米传感器解决方案
Anal Sci Adv. 2025 Feb 17;6(1):e70000. doi: 10.1002/ansa.70000. eCollection 2025 Jun.
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Concurrent Onset of Osimertinib-Induced Heart Failure and Metronidazole-Induced Encephalopathy During Brain Abscess Treatment: A Report of a Rare Case.

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1
Metronidazole retention enema in the management of severe intestinal amoebiasis.
Niger Med J. 1976 Jan;6(1):2-8.
2
Absorption and excretion of metronidazole. I. Serum concentration and urinary excretion after oral administration.甲硝唑的吸收与排泄。I. 口服给药后的血清浓度及尿排泄情况。
Br J Vener Dis. 1961 Dec;37(4):273-5. doi: 10.1136/sti.37.4.273.
3
Use of metronidazole in the treatment of trichomoniasis.
Am J Obstet Gynecol. 1962 May 15;83:1284-7. doi: 10.1016/s0002-9378(16)36036-7.
4
脑脓肿治疗期间奥希替尼诱发心力衰竭与甲硝唑诱发脑病同时发生:1例罕见病例报告
Cureus. 2024 Dec 4;16(12):e75079. doi: 10.7759/cureus.75079. eCollection 2024 Dec.
4
The Blood-Brain Barrier and Pharmacokinetic/Pharmacodynamic Optimization of Antibiotics for the Treatment of Central Nervous System Infections in Adults.血脑屏障与治疗成人中枢神经系统感染抗生素的药代动力学/药效学优化
Antibiotics (Basel). 2022 Dec 19;11(12):1843. doi: 10.3390/antibiotics11121843.
5
The novel use of oral antibiotic monotherapy in prosthetic valve endocarditis caused by Finegoldia magna: a case study.口腔抗生素单药疗法在巨大芬戈尔德菌引起的人工瓣膜心内膜炎中的新应用:一项病例研究。
J Cardiothorac Surg. 2019 Sep 18;14(1):170. doi: 10.1186/s13019-019-0993-9.
6
Clinical efficacy of 12-h metronidazole dosing regimens in patients with anaerobic or mixed anaerobic infections.甲硝唑12小时给药方案治疗厌氧或混合厌氧感染患者的临床疗效。
Ther Adv Infect Dis. 2018 May;5(3):57-62. doi: 10.1177/2049936118766462. Epub 2018 Apr 3.
7
Applied Concepts in PBPK Modeling: How to Extend an Open Systems Pharmacology Model to the Special Population of Pregnant Women.应用于群体药代动力学模型的概念:如何将开放系统药理学模型扩展到孕妇这一特殊人群。
CPT Pharmacometrics Syst Pharmacol. 2018 Jul;7(7):419-431. doi: 10.1002/psp4.12300. Epub 2018 Apr 20.
8
Metronidazole-induced encephalopathy in a patient with end-stage liver disease.一名终末期肝病患者发生甲硝唑诱发的脑病。
Case Reports Hepatol. 2012;2012:209258. doi: 10.1155/2012/209258. Epub 2012 Dec 17.
9
Oral metronidazole as antibiotic prophylaxis for patients with nonperforated appendicitis.口服甲硝唑作为非穿孔性阑尾炎患者的抗生素预防用药。
Clin Exp Gastroenterol. 2011;4:273-6. doi: 10.2147/CEG.S18153. Epub 2011 Dec 7.
10
The effects of an investigational antimalarial agent, NIPRD-AM1 on the single dose pharmacokinetics of metronidazole in healthy human volunteers.
Eur J Drug Metab Pharmacokinet. 2011 Jan;35(3-4):103-8. doi: 10.1007/s13318-010-0012-y. Epub 2010 Oct 12.
Further observations on metronidazole (Flagyl).关于甲硝唑(灭滴灵)的进一步观察
Br J Vener Dis. 1961 Dec;37(4):278-9. doi: 10.1136/sti.37.4.278.
5
Laboratory studies with the systemic trichomonacide, metronidazole.使用全身性滴虫杀灭剂甲硝唑的实验室研究。
J Clin Pathol. 1961 Jul;14(4):431-5. doi: 10.1136/jcp.14.4.431.
6
Pharmacokinetics of Metronidazole in pregnant women.
Chemotherapy. 1981;27(2):73-9. doi: 10.1159/000237958.
7
High-dose metronidazole: pharmacokinetics and bioavailability using an iv preparation and application of its use as a radiosensitizer.
Cancer Treat Rep. 1980 Oct-Nov;64(10-11):1087-95.
8
Metronidazole in breast milk.
Obstet Gynecol. 1981 Jan;57(1):48-50.
9
Pharmacokinetics of metronidazole in healthy adult volunteers after tablets and suppositories.
Chemotherapy. 1980;26(4):231-41. doi: 10.1159/000237911.
10
Serum metronidazole levels following rectal administration.
J Antimicrob Chemother. 1981 Nov;8(5):424-5. doi: 10.1093/jac/8.5.424.