Mathru M, Rao T L, Venus B
Crit Care Med. 1983 May;11(5):359-61. doi: 10.1097/00003246-198305000-00008.
Retrospective analysis of pulmonary barotrauma incidence in 292 patients ventilated greater than or equal to 24 h was conducted. From 1971-1973, 156 patients with acute respiratory insufficiency were managed with controlled mechanical ventilation (CMV) and PEEP. During 1973-1976, 136 patients were supported with IMV and CPAP. Despite higher mean peak and end-expiratory airway pressure, the IMV-CPAP group exhibited a significantly lower incidence of ventilator-induced barotrauma; 7% vs 22% (p less than 0.01). We suspect the difference is related to fewer mechanical breaths with IMV and not to the level of end-expiratory pressure employed.
对292例机械通气时间大于或等于24小时的患者的肺气压伤发生率进行了回顾性分析。1971年至1973年,156例急性呼吸功能不全患者采用控制机械通气(CMV)和呼气末正压通气(PEEP)进行治疗。1973年至1976年,136例患者采用间歇指令通气(IMV)和持续气道正压通气(CPAP)进行支持治疗。尽管IMV-CPAP组的平均峰值气道压和呼气末气道压较高,但其呼吸机诱导的气压伤发生率显著较低;分别为7%和22%(p<0.01)。我们怀疑这种差异与IMV时机械通气次数较少有关,而与所采用的呼气末压力水平无关。