Czarnetzki B M
Dermatologica. 1983;166(1):44-7. doi: 10.1159/000249832.
10 adult patients with symptomatic urticaria pigmentosa were treated with ketotifen versus placebo in a double-blind cross-over study. A highly significant reduction of the daily symptom scores for pruritus and whealing was found with 2 mg ketotifen daily per os, and, compared to oral disodium cromoglycate, ketotifen was much more effective. Tiredness was the only side effect noted in 40% of the patients, and a transient worsening of symptoms was noted after discontinuation of the drug.
在一项双盲交叉研究中，对10例有症状的色素性荨麻疹成年患者使用酮替芬与安慰剂进行治疗。发现每日口服2毫克酮替芬可使瘙痒和风团的每日症状评分显著降低，并且与口服色甘酸钠相比，酮替芬的效果要好得多。40%的患者出现的唯一副作用是疲倦，停药后症状出现短暂加重。
