Schuhl J F, Holgado de Cuesta D
Clin Allergy. 1981 Jul;11(4):401-5. doi: 10.1111/j.1365-2222.1981.tb01611.x.
A double-blind non crossover trial comparing disodium cromoglycate (DSCG), with ketotifen, was carried out in twenty-seven extrinsic asthmatic children over 12 weeks. Assessment was made using symptom score and drug score charts. Both drugs showed a similar protective effect in the group studied. None of the subjects had to withdraw from the trial and no side-effects were noted in weight-curve, arterial pressure and pulse rate. PEFR values remained unchanged for both drugs throughout the trial. A non-significant tendency for additional corticosteroid support in the Ketotifen group was noted.
一项针对27名12岁以上外源性哮喘儿童进行的为期12周的双盲非交叉试验，比较了色甘酸钠（DSCG）和酮替芬。使用症状评分表和药物评分表进行评估。在研究组中，两种药物均显示出相似的保护作用。没有受试者退出试验，在体重曲线、动脉压和脉搏率方面未观察到副作用。在整个试验过程中，两种药物的呼气峰流速（PEFR）值均保持不变。注意到酮替芬组有额外使用皮质类固醇支持的非显著趋势。
