Samoszuk M, Kaplan E, Finkle H I
Ther Drug Monit. 1983;5(1):113-6. doi: 10.1097/00007691-198303000-00012.
The reliability of two clinical laboratory methods for assaying theophylline in serum is compared. Analysis of serum-based standards and 70 patient specimens by rate nephelometric inhibition immunoassay (NIIA) and by high-performance liquid chromatography (HPLC) demonstrates that both methods have comparable random analytical variation. The results indicate that NIIA is a reliable method for measuring serum theophylline and may serve as a practical alternative to the HPLC method.
比较了两种临床实验室方法测定血清中茶碱的可靠性。通过速率散射比浊抑制免疫测定法（NIIA）和高效液相色谱法（HPLC）对基于血清的标准品和70份患者标本进行分析，结果表明这两种方法具有相当的随机分析变异。结果表明，NIIA是一种测定血清茶碱的可靠方法，可作为HPLC法的实用替代方法。
