Guss R B, Koenig S, De La Pena W, Marx M, Kaufman H E
Am J Ophthalmol. 1983 May;95(5):651-8. doi: 10.1016/0002-9394(83)90385-9.
Of 445 eyes (305 of which were aphakic) that underwent penetrating keratoplasty, 11 developed endophthalmitis, three immediately after surgery, two after subsequent secondary surgery, and six after late ulceration of the transplanted cornea. The diagnosis was based clinically on the loss of the red reflex and vitreous opacification, and was confirmed by culture of vitreous aspirate. All patients who developed endophthalmitis were aphakic and had received corticosteroids at the time of infection; most had undergone previous ocular surgery. These patients differed from those previously described with this condition because neither the donor tissue nor the storage medium was the source of infection. Treatment included intracameral, systemic, and topical administration of antibiotics. When the endophthalmitis originated from a corneal ulcer in a graft, the infected tissue was replaced with a new transplant. Despite treatment, the final visual outcomes were not good. One eye had a final visual acuity of 20/200 and one eye had a final visual acuity of 20/400. Three eyes had light perception and six eyes had no light perception. One eye was eventually enucleated.
在接受穿透性角膜移植术的445只眼中（其中305只为无晶状体眼），有11只发生了眼内炎，3只在手术后立即发生，2只在随后的二次手术后发生，6只在移植角膜晚期溃疡后发生。诊断临床上基于红光反射消失和玻璃体混浊，并通过玻璃体抽吸物培养得以证实。所有发生眼内炎的患者均为无晶状体眼，且在感染时接受了皮质类固醇治疗；大多数患者此前接受过眼科手术。这些患者与先前描述的患有这种疾病的患者不同，因为供体组织和储存介质都不是感染源。治疗包括前房内、全身和局部使用抗生素。当眼内炎起源于移植角膜的溃疡时，感染组织被新的移植组织替代。尽管进行了治疗，但最终视力结果并不理想。一只眼的最终视力为20/200，一只眼的最终视力为20/400。三只眼有光感，六只眼无光感。一只眼最终被摘除。
