Friedman A
Neurol Neurochir Pol. 1978 Jan-Feb;12(1):39-43.
The therapeutic effectiveness of a L-DOPA preparation of sustained action was established in 9 patients with parkinsonism on the basis of a neurological parkinsonism scale and Northwestern University Disability Scale. The investigations were carried out by the method of cross test with conventional L-DOPA preparation (Larodopa). In these investigations no higher effectiveness of the retard form was shown. Side effects during administration of the retard form were more frequent and more intense than during administration of the conventional drug.
基于帕金森病神经量表和西北大学残疾量表,对9例帕金森病患者确定了一种长效左旋多巴制剂的治疗效果。采用与传统左旋多巴制剂(美多巴)交叉试验的方法进行研究。在这些研究中,未显示缓释剂型有更高的疗效。与使用传统药物相比,使用缓释剂型时副作用更频繁、更严重。