Domzal T, Pakszys W, Domzal B, Ligezińska B
Neurol Neurochir Pol. 1976 Sep-Oct;10(5):637-43.
The results of substitutive treatment of Parkinson's disease with L-dopa were assessed using a special chart for periodical examinations. This chart contains, among others, a 100-point scoring scale of parkinsonian disability which makes possible objective comparison of the condition of patients after various duration of treatment. The obtained results were compared according to age, sex, duration of disease, results of previous anticholinergic treatment. Ophthalmological examinations were carried out determining the width and reactions of pupils, accomodation and intraocular tension as well as side effects. The results of scoring demonstrated a high therapeutic effectiveness of L-dopa, lack of significant ophthalmological abnormalities and mild degree of side effects due to peripheral and autonomic-system reactions to L-dopa.
使用定期检查专用图表评估左旋多巴替代治疗帕金森病的结果。该图表除其他内容外，还包含帕金森病残疾程度的100分评分量表，这使得能够客观比较不同治疗时长后患者的病情。根据年龄、性别、病程、先前抗胆碱能治疗结果对所得结果进行比较。进行眼科检查以确定瞳孔宽度和反应、调节功能和眼压以及副作用。评分结果显示左旋多巴具有很高的治疗效果，没有明显的眼科异常，且因外周和自主神经系统对左旋多巴的反应而导致的副作用程度较轻。
