Eisenfeld L, Ermocilla R, Wirtschafter D, Cassady G
Am J Dis Child. 1983 Jul;137(7):645-9. doi: 10.1001/archpedi.1983.02140330029008.
Bacterial were identified in 126 blood and CSF cultures obtained in 311 consecutive neonatal deaths (41%). These postmortem cultures were of diagnostic value, providing the sole means for definitive bacteriologic diagnosis in 82 (65%) of the 126 infected infants. Similarity of organisms found in specimens before and after death (identical in 25 of 26), similar identity of organisms identified by histologic Gram's stain and culture (the same in 48 of 49), and the identical nature of organisms identified from blood and CSF sites (the same in 43 of 43) support the validity of these cultures. Bacterial infection remains a serious problem in neonatal intensive care. The scope of this problem may be underestimated if postmortem cultures are not obtained.
在311例连续新生儿死亡病例（占41%）中采集的126份血液和脑脊液培养样本中发现了细菌。这些尸检培养样本具有诊断价值，为126例受感染婴儿中的82例（占65%）提供了确诊细菌学诊断的唯一手段。生前和死后标本中发现的微生物的相似性（26例中有25例相同）、组织学革兰氏染色和培养鉴定的微生物的相似同一性（49例中有48例相同）以及从血液和脑脊液部位鉴定的微生物的相同性质（43例中有43例相同）支持了这些培养结果的有效性。细菌感染在新生儿重症监护中仍然是一个严重问题。如果不进行尸检培养，这个问题的范围可能会被低估。
