Olson D P, South P J, Hendrix K
Am J Vet Res. 1983 Apr;44(4):577-82.
Serum chemical values were determined in cold-stressed Holstein bull calves ranging from 1 to 7 days of age. The animals were anesthetized and cold-stressed until their core body temperature (colonic) was lowered 10 C. Animals were then rewarmed in warm water, with heat pads or heat lamps, or were allowed to recover naturally (unassisted) at room temperature. Blood samples were collected at selected intervals during cooling and recovery. Increases (P less than 0.05) were observed in the concentrations of glucose, calcium, phosphorus, iron, alkaline phosphatase, aspartate aminotransferase, lactate dehydrogenase, total protein, albumin, total globulin, serum urea nitrogen, uric acid, total bilirubin, indirect bilirubin, and cholesterol in the cold-stressed calves during cooling. Concentrations of chloride and insulin decreased (P less than 0.05) during the same period. Changes observed in many of the serum chemical values during rewarming were generally the reverse of the respective changes that occurred during cooling, although insulin values became exceedingly high in some cases midway or near the end of recovery. Serum enzyme values also remained high during most of recovery. Data did not indicate a clear advantage of one method of rewarming over the other methods used in terms of return of the serum chemical values to normal.
对1至7日龄的荷斯坦公牛犊进行冷应激处理后，测定其血清化学值。将动物麻醉并进行冷应激处理，直到其核心体温（结肠温度）降低10摄氏度。然后，将动物置于温水中复温，或使用加热垫或加热灯复温，或者让它们在室温下自然恢复（无辅助）。在降温及恢复过程中的选定时间间隔采集血样。在冷应激犊牛降温过程中，观察到葡萄糖、钙、磷、铁、碱性磷酸酶、天冬氨酸氨基转移酶、乳酸脱氢酶、总蛋白、白蛋白、总球蛋白、血清尿素氮、尿酸、总胆红素、间接胆红素和胆固醇的浓度升高（P<0.05）。同期氯化物和胰岛素浓度降低（P<0.05）。复温过程中许多血清化学值的变化通常与降温过程中各自的变化相反，尽管在某些情况下，胰岛素值在恢复中期或接近恢复结束时变得极高。在大多数恢复过程中血清酶值也保持较高水平。数据并未表明在使血清化学值恢复正常方面，一种复温方法比其他使用的方法具有明显优势。
