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正常成年沙鼠甲状腺中C细胞降钙素分布的免疫细胞研究。

Immunocytological study of the distribution of C-cells calcitonin in the thyroid gland of the normal adult gerbil.

作者信息

Guilloteau D, Fetissof F, Renjard L, Dubois M P, Besnard J C

出版信息

Experientia. 1983 Aug 15;39(8):876-8. doi: 10.1007/BF01990414.

DOI:10.1007/BF01990414
PMID:6347706
Abstract

The distribution of C-cells in the thyroid gland of the gerbil (Meriones inguiculatus) was studied on serial sections in the cranio-caudal direction. C-cells were visualized by immunofluorescence with an anti-calcitonin immune serum. A very heterogeneous distribution was found. C-cells first appear in the posterio-interior position. Then they progressively occupy the whole posterior part and finally are confined to the posterio-exterior position. No C-cells at all were detected in the upper and lower poles. According to the species, there is a wide variation in the relative distribution of C-cells in the thyroid gland. Our results add to the information available about the distribution of C-cells and its bearing on phylogenic evolution.

摘要

采用沿颅尾方向的连续切片,对长爪沙鼠(Meriones inguiculatus)甲状腺中C细胞的分布进行了研究。使用抗降钙素免疫血清通过免疫荧光法使C细胞可视化。结果发现其分布极不均匀。C细胞最初出现在后内侧位置。然后它们逐渐占据整个后部,最终局限于后外侧位置。在上极和下极未检测到任何C细胞。根据物种不同,甲状腺中C细胞的相对分布存在很大差异。我们的研究结果补充了有关C细胞分布及其系统发育进化关系的现有信息。

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1
Immunocytological study of the distribution of C-cells calcitonin in the thyroid gland of the normal adult gerbil.正常成年沙鼠甲状腺中C细胞降钙素分布的免疫细胞研究。
Experientia. 1983 Aug 15;39(8):876-8. doi: 10.1007/BF01990414.
2
Immunofluorescent localization of calcitonin in the ultimobranchial gland of Rana temporaria and Rana pipiens.
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J Clin Endocrinol Metab. 1975 Dec;41(06):1076-81. doi: 10.1210/jcem-41-6-1076.
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[Immunocytological studies of C cells with anti-calcitonin or antisomatostatin immunoserums in rats treated with vitamin D, thyroxine or benzyl-thiouracil].[用抗降钙素或抗生长抑素免疫血清对经维生素D、甲状腺素或苄基硫脲嘧啶处理的大鼠C细胞进行免疫细胞学研究]
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Calcitonin cells and unusual follicle in four month old wistar rats.四个月大的Wistar大鼠中的降钙素细胞和异常滤泡。
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本文引用的文献

1
CALCITONIN PRODUCTION AND THE MITOCHONDRION-RICH CELLS OF THE DOG THYROID.降钙素的产生与犬甲状腺富含线粒体的细胞
Nature. 1964 Sep 5;203:1029-30. doi: 10.1038/2031029a0.
2
Evidence for calcitonin in the thyroid gland of normal and anencephalic human fetuses: immunocytological localization, radioimmunoassay, and gel filtration of thyroid extracts.正常和无脑儿人类胎儿甲状腺中降钙素的证据:免疫细胞定位、放射免疫测定及甲状腺提取物的凝胶过滤
J Clin Endocrinol Metab. 1980 Feb;50(2):316-21. doi: 10.1210/jcem-50-2-316.
3
Quantitation of proliferative mucosal cells of the Mongolian gerbil on a weight basis.
以重量为基础对长爪沙鼠增殖性黏膜细胞进行定量分析。
Experientia. 1982 Aug 15;38(8):986-7. doi: 10.1007/BF01953693.
4
Oncogenic studies on the Mongolian gerbil.
Cancer Res. 1966 May;26(5):844-7.
5
Influence of intestinal mucosal renewal rate on development of gastrointestinal injury and survival time of irradiated gerbils.肠道黏膜更新率对辐照沙鼠胃肠道损伤发展及存活时间的影响
Radiat Res. 1972 Feb;49(2):367-80.
6
Intestinal cell transit time in the Mongolian gerbil, Meriones unguiculatus.长爪沙鼠(Meriones unguiculatus)的肠道细胞转运时间。
Experientia. 1974 Apr 15;30(4):344-5. doi: 10.1007/BF01921653.
7
Immunocytochemical confirmation of the neural crest origin of avian calcitonin-producing cells.鸟类降钙素产生细胞神经嵴起源的免疫细胞化学证实
Histochemistry. 1974;40(3):209-14. doi: 10.1007/BF00501955.
8
The ultimobranchial origin of calcitonin.降钙素的终末鳃后体起源。
Lancet. 1968 Jan 20;1(7534):108-10. doi: 10.1016/s0140-6736(68)92720-7.
9
Distribution of calcitonin-containing cells in the normal adult human thyroid gland: a correlation of morphology with peptide content.正常成人甲状腺中降钙素细胞的分布:形态与肽含量的相关性
J Clin Endocrinol Metab. 1974 Apr;38(4):688-94. doi: 10.1210/jcem-38-4-688.
10
Specific carcinogenic effect of N-methyl-N-nitrosourea on the midventral sebaceous gland of the gerbil (Meriones unguiculatus).N-甲基-N-亚硝基脲对沙鼠(长爪沙鼠)腹中部皮脂腺的特定致癌作用。
J Natl Cancer Inst. 1975 Sep;55(3):637-40. doi: 10.1093/jnci/55.3.637.