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摩根氏变形杆菌与泌尿系统感染的关联不如奇异变形杆菌频繁——一种解释。

Proteus morgani is less frequently associated with urinary tract infections than Proteus mirabilis--an explanation.

作者信息

Senior B W

出版信息

J Med Microbiol. 1983 Aug;16(3):317-22. doi: 10.1099/00222615-16-3-317.

Abstract

The metabolic activities of faecal and urinary strains of Proteus morgani and P. mirabilis were compared. Regardless of origin, the generation time of P. morgani strains in urine was approximately twice as long as that of the P. mirabilis strains. Urease synthesis was constitutive in P. morgani strains but required induction with urea in the P. mirabilis strains. In the presence of urea, the P. mirabilis strains liberated ammonia more rapidly and produced alkaline conditions more quickly than P. morgani strains, although they synthesized much less urease. These characteristics may place P. morgani strains at a disadvantage in comparison with P. mirabilis strains in their ability to cause urinary tract infections.

摘要

对摩根氏变形杆菌和奇异变形杆菌的粪便菌株及尿液菌株的代谢活性进行了比较。无论来源如何,摩根氏变形杆菌菌株在尿液中的代时约为奇异变形杆菌菌株的两倍。脲酶合成在摩根氏变形杆菌菌株中是组成型的,但奇异变形杆菌菌株需要用尿素诱导。在有尿素存在的情况下,奇异变形杆菌菌株比摩根氏变形杆菌菌株更迅速地释放氨并更快地产生碱性条件,尽管它们合成的脲酶要少得多。与奇异变形杆菌菌株相比,这些特性可能使摩根氏变形杆菌菌株在引起尿路感染的能力方面处于劣势。

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