Kindler J, Sieberth H G, Hahn R, Glöckner W M, Vlaho M, Pelzer R
Proc Eur Dial Transplant Assoc. 1983;19:168-74.
A retrospective study of 332 dialysis patients (observation period up to 17 years) demonstrated that cardiovascular and cerebrovascular death rates due to atherosclerosis did not increase with length of time on dialysis. Data analysis showed that cardiovascular and cerebrovascular morbidity and mortality during dialysis is primarily caused by high blood pressure existing prior to commencement of dialysis and an unfavourable very low-density lipoprotein/high-density lipoprotein (VLDL/HDL) cholesterol quotient at the beginning of dialysis treatment. The treatment of the patient before acceptance onto dialysis seems therefore to be the determining factor in the prognosis on dialysis.
一项对332名透析患者(观察期长达17年)的回顾性研究表明,因动脉粥样硬化导致的心血管和脑血管死亡率并未随着透析时间的延长而增加。数据分析显示,透析期间的心血管和脑血管发病率及死亡率主要是由透析开始前就已存在的高血压以及透析治疗开始时不利的极低密度脂蛋白/高密度脂蛋白(VLDL/HDL)胆固醇比值所致。因此,患者在接受透析治疗前的治疗情况似乎是透析预后的决定性因素。