Suppr超能文献

正常和裸鼠大鼠骨髓培养物中黏膜肥大细胞生长的刺激作用。

Stimulation of mucosal mast cell growth in normal and nude rat bone marrow cultures.

作者信息

Haig D M, McMenamin C, Gunneberg C, Woodbury R, Jarrett E E

出版信息

Proc Natl Acad Sci U S A. 1983 Jul;80(14):4499-503. doi: 10.1073/pnas.80.14.4499.

DOI:10.1073/pnas.80.14.4499
PMID:6348770
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC384066/
Abstract

Mast cells with the morphological and biochemical properties of mucosal mast cells (MMC) appear and proliferate to form the predominant cell type in rat bone marrow cultures stimulated with factors from antigen- or mitogen-activated lymphocytes. Conditioned media causing a selective proliferation of MMC were derived from mesenteric lymph node cells of Nippostrongylus brasiliensis-infected rats restimulated in vitro with specific antigen or from normal or infected rat mesenteric lymph node cells stimulated with concanavalin A. MMC growth factor is not produced by T-cell-depleted mesenteric lymph node cells or by the mesenteric lymph node cells of athymic rats. By contrast, MMC precursors are present in the bone marrow of athymic rats and are normally receptive to the growth factor produced by the lymphocytes of thymus-intact rats. The thymus dependence of MMC hyperplasia is thus based on the requirement of a thymus-independent precursor for a T-cell-derived growth promoter.

摘要

具有黏膜肥大细胞（MMC）形态和生化特性的肥大细胞出现并增殖，成为在由抗原或丝裂原激活的淋巴细胞产生的因子刺激的大鼠骨髓培养物中的主要细胞类型。导致MMC选择性增殖的条件培养基来自用特定抗原在体外再次刺激的巴西日圆线虫感染大鼠的肠系膜淋巴结细胞，或来自用刀豆球蛋白A刺激的正常或感染大鼠的肠系膜淋巴结细胞。MMC生长因子不是由去除T细胞的肠系膜淋巴结细胞或无胸腺大鼠的肠系膜淋巴结细胞产生的。相比之下，MMC前体存在于无胸腺大鼠的骨髓中，并且通常对胸腺完整大鼠的淋巴细胞产生的生长因子有反应。因此，MMC增生的胸腺依赖性基于非胸腺依赖性前体对T细胞衍生的生长促进剂的需求。

相似文献

1
Stimulation of mucosal mast cell growth in normal and nude rat bone marrow cultures.正常和裸鼠大鼠骨髓培养物中黏膜肥大细胞生长的刺激作用。
Proc Natl Acad Sci U S A. 1983 Jul;80(14):4499-503. doi: 10.1073/pnas.80.14.4499.
2
In vitro studies on mast cell proliferation in N. brasiliensis infection.巴西日圆线虫感染中肥大细胞增殖的体外研究。
Immunology. 1984 Apr;51(4):643-51.
3
Bone marrow origin of mucosal mast cells.黏膜肥大细胞的骨髓起源。
Int Arch Allergy Appl Immunol. 1984;73(3):242-7. doi: 10.1159/000233476.
4
Thymus dependence of the adoptive transfer of intestinal mastocytopoiesis in Trichinella spiralis-infected mice.旋毛虫感染小鼠肠道肥大细胞生成的过继转移对胸腺的依赖性
Int Arch Allergy Appl Immunol. 1982;68(3):260-7. doi: 10.1159/000233109.
5
Rat IL-3 stimulates the growth of rat mucosal mast cells in culture.大鼠白细胞介素-3可刺激培养中的大鼠黏膜肥大细胞生长。
Immunology. 1988 Oct;65(2):205-11.
6
Bromodeoxyuridine labeling studies on the proliferation of intestinal mucosal mast cells in normal and athymic rats.溴脱氧尿苷标记研究正常和无胸腺大鼠肠道黏膜肥大细胞的增殖情况。
APMIS. 1990 Apr;98(4):369-76. doi: 10.1111/j.1699-0463.1990.tb01046.x.
7
Functional characterization of mast cells generated in vitro from the mesenteric lymph node of rats infected with Nippostrongylus brasiliensis.从感染巴西日圆线虫的大鼠肠系膜淋巴结体外生成的肥大细胞的功能特性
Immunology. 1986 Mar;57(3):455-9.
8
The effect of dexamethasone on growth and differentiation of bone-marrow derived mucosal mast cells in vitro.地塞米松对体外培养的骨髓源性黏膜肥大细胞生长和分化的影响。
Immunology. 1987 Sep;62(1):29-34.
9
Surface phenotype of T cells producing growth of mucosal mast cells in normal rat bone marrow culture.在正常大鼠骨髓培养中产生黏膜肥大细胞生长的T细胞的表面表型。
Immunology. 1985 Jul;55(3):399-403.
10
Infection with Nippostrongylus brasiliensis induces invasion of mast cell precursors from peripheral blood to small intestine.感染巴西日圆线虫会诱导肥大细胞前体从外周血侵入小肠。
Blood. 1995 Mar 1;85(5):1334-40.

引用本文的文献

1
Effects of IL-3 and SCF on Histamine Production Kinetics and Cell Phenotype in Rat Bone Marrow-derived Mast Cells.IL-3 和 SCF 对大鼠骨髓来源肥大细胞组氨酸产生动力学和细胞表型的影响。
Immune Netw. 2010 Feb;10(1):15-25. doi: 10.4110/in.2010.10.1.15. Epub 2010 Feb 28.
2
Rat bone marrow-derived mast cells co-cultured with 3T3 fibroblasts in the absence of T-cell derived cytokines require stem cell factor for their survival and maintain their mucosal mast cell-like phenotype.在没有T细胞衍生细胞因子的情况下，与3T3成纤维细胞共培养的大鼠骨髓来源肥大细胞需要干细胞因子来维持其存活并保持其黏膜肥大细胞样表型。
Immunology. 1996 Jul;88(3):375-83. doi: 10.1046/j.1365-2567.1996.d01-664.x.
3
Stem cell factor enhances immunoglobulin E-dependent mediator release from cultured rat bone marrow-derived mast cells: activation of previously unresponsive cells demonstrated by a novel ELISPOT assay.干细胞因子增强培养的大鼠骨髓来源肥大细胞中免疫球蛋白E依赖的介质释放：通过一种新型ELISPOT检测法证明对先前无反应细胞的激活。
Immunology. 1996 Feb;87(2):326-33. doi: 10.1046/j.1365-2567.1996.455545.x.
4
In vitro studies on mast cell proliferation in N. brasiliensis infection.巴西日圆线虫感染中肥大细胞增殖的体外研究。
Immunology. 1984 Apr;51(4):643-51.
5
Surface phenotype of T cells producing growth of mucosal mast cells in normal rat bone marrow culture.在正常大鼠骨髓培养中产生黏膜肥大细胞生长的T细胞的表面表型。
Immunology. 1985 Jul;55(3):399-403.
6
Homology of the rat basophilic leukemia cell and the rat mucosal mast cell.大鼠嗜碱性白血病细胞与大鼠黏膜肥大细胞的同源性。
Proc Natl Acad Sci U S A. 1985 Jun;82(11):3871-5. doi: 10.1073/pnas.82.11.3871.
7
Phenotypic analysis of mast cell granule proteinases in normal rat bone marrow cultures.正常大鼠骨髓培养物中肥大细胞颗粒蛋白酶的表型分析。
Immunology. 1987 Jan;60(1):147-9.
8
The effect of dexamethasone on growth and differentiation of bone-marrow derived mucosal mast cells in vitro.地塞米松对体外培养的骨髓源性黏膜肥大细胞生长和分化的影响。
Immunology. 1987 Sep;62(1):29-34.
9
Histochemical heterogeneity of dermal mast cells in athymic and normal rats.无胸腺大鼠和正常大鼠皮肤肥大细胞的组织化学异质性
Histochem J. 1988 Jan;20(1):19-28. doi: 10.1007/BF01745965.
10
Rat IL-3 stimulates the growth of rat mucosal mast cells in culture.大鼠白细胞介素-3可刺激培养中的大鼠黏膜肥大细胞生长。
Immunology. 1988 Oct;65(2):205-11.

本文引用的文献

1
Nature of the thymus dependency of mucosal mast cells. III. Mucosal mast cells in nude mice and nude rats, in B rats and in a child with the Di George syndrome.黏膜肥大细胞胸腺依赖性的本质。III. 裸鼠、裸大鼠、B大鼠及一名患有迪格奥尔格综合征儿童体内的黏膜肥大细胞
Int Arch Allergy Appl Immunol. 1981;64(3):320-31. doi: 10.1159/000232710.
2
Thymus dependence of the adoptive transfer of intestinal mastocytopoiesis in Trichinella spiralis-infected mice.旋毛虫感染小鼠肠道肥大细胞生成的过继转移对胸腺的依赖性
Int Arch Allergy Appl Immunol. 1982;68(3):260-7. doi: 10.1159/000233109.
3
Long-term in vitro culture of murine mast cells. I. Description of a growth factor-dependent culture technique.小鼠肥大细胞的长期体外培养。I. 一种依赖生长因子的培养技术的描述。
J Immunol. 1981 Aug;127(2):788-94.
4
Generation of mucosal mast cells is stimulated in vitro by factors derived from T cells of helminth-infected rats.来自感染蠕虫大鼠的T细胞衍生因子可在体外刺激黏膜肥大细胞的生成。
Nature. 1982 Nov 11;300(5888):188-90. doi: 10.1038/300188a0.
5
Committed T lymphocyte stem cells of rats. Characterization by surface W3/13 antigen and radiosensitivity.大鼠定向T淋巴细胞干细胞。通过表面W3/13抗原及放射敏感性进行特性鉴定。
J Exp Med. 1981 Oct 1;154(4):1164-77. doi: 10.1084/jem.154.4.1164.
6
The persisting (P) cell: histamine content, regulation by a T cell-derived factor, origin from a bone marrow precursor, and relationship to mast cells.持久（P）细胞：组胺含量、受T细胞衍生因子的调节、起源于骨髓前体细胞以及与肥大细胞的关系。
Proc Natl Acad Sci U S A. 1981 Jan;78(1):323-7. doi: 10.1073/pnas.78.1.323.
7
Regulatory role of IgE-binding factors from rat T lymphocytes. II. Glycoprotein nature and source of IgE-potentiating factor.大鼠T淋巴细胞中IgE结合因子的调节作用。II. IgE增强因子的糖蛋白性质及来源。
J Immunol. 1980 Oct;125(4):1436-41.
8
Culture from mouse bone marrow of a subclass of mast cells possessing a distinct chondroitin sulfate proteoglycan with glycosaminoglycans rich in N-acetylgalactosamine-4,6-disulfate.来自小鼠骨髓的一种肥大细胞亚类的培养物，该亚类具有一种独特的硫酸软骨素蛋白聚糖，其糖胺聚糖富含N-乙酰半乳糖胺-4,6-二硫酸盐。
J Biol Chem. 1982 Jun 25;257(12):7229-36.
9
Studies on the immunobiology of rnu/rnu "nude" rats with congenital aplasia of the thymus.先天性胸腺发育不全的rnu/rnu“裸”大鼠免疫生物学研究。
Eur J Immunol. 1980 Jan;10(1):58-65. doi: 10.1002/eji.1830100112.
10
Production and activities of IgE in helminth infection.蠕虫感染中IgE的产生与活性。
Prog Allergy. 1982;31:178-233.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验