Schneider H, Krahn J
Prakt Anaesth. 1978 Feb;13(1):59-62.
Narcots and muscle relaxants are proven causes of malignant hyperthermia. Alcohol and a large number of drugs are capable of inducing myopathic changes which resemble malignant hyperthermia. The case of a 47-year-old man is reported who presented with the clinical symptoms of maligant hyperthermia. The similarity in the course of the disturbance, the clinical and chemical findings and the changes in the morphological features of the muscle suggested that the abnormally high body temperature had been induced by psychotropic durgs in a pre-disposed patient with an history of chronic alcoholism.
麻醉剂和肌肉松弛剂已被证实是恶性高热的病因。酒精和大量药物能够诱发类似于恶性高热的肌病变化。本文报告了一名47岁男性患者的病例,该患者表现出恶性高热的临床症状。疾病过程、临床和化学检查结果以及肌肉形态特征的变化相似,提示在一名有慢性酒精中毒病史的易感患者中,精神药物诱发了异常高体温。