Schneider V, Bratzke H
Z Rechtsmed. 1983;90(1):71-80. doi: 10.1007/BF01886069.
A case of symptomatic malignant hyperthermia is reported involving a 35-year-old man who suffered a serious cerebral injury after a gunshot to the head and who died from hyperthermia (41.5 degrees C) and tachycardia 1.5 days after dental treatment under general anesthesia. The sceletal muscles did not show any changes that would indicate a myopathy, the CPL value was normal, there was also no familial factor in this case. It is taken as an opportunity here to point out that such a case must not end fatally since there is a drug on the market in the meantime (Dantrolen) which is to be administered i.v. This medication acts causally on the membrane disturbances (release of calcium ions by appropriate trigger substances) which are the underlying cause of the malignant hyperthermia.
报告了一例症状性恶性高热病例，患者为一名35岁男性，头部遭枪击后受重伤，在全身麻醉下接受牙科治疗1.5天后死于高热（41.5摄氏度）和心动过速。骨骼肌未显示出任何表明存在肌病的变化，CPL值正常，该病例也不存在家族因素。借此机会指出，这样的病例不一定会致命，因为市场上已有一种药物（丹曲林）可供静脉注射。这种药物可针对膜紊乱（由适当触发物质释放钙离子）发挥作用，而膜紊乱正是恶性高热的根本原因。
