Wertheimer S J, Leifer Z
Biochem Biophys Res Commun. 1983 Jul 29;114(2):882-8. doi: 10.1016/0006-291x(83)90863-x.
Cells of Escherichia coli grown under physiological (noninducing) conditions have a low level of lysine decarboxylase activity. This activity differs from the enzyme found in induced cells in its sensitivity to putrescine (33% of control in the presence of 20 mM putrescine). It is also sensitive to spermidine (20% of control in the presence of 6 mM spermidine). A mixture of putrescine and spermidine completely eliminated lysine decarboxylase activity. This provides evidence for the existence of a biosynthetic enzyme and suggests a mechanism to explain the appearance of cadaverine in polyamine-depleted cells.
在生理（非诱导）条件下生长的大肠杆菌细胞具有低水平的赖氨酸脱羧酶活性。这种活性与诱导细胞中发现的酶在对腐胺的敏感性方面有所不同（在20 mM腐胺存在下为对照的33%）。它对亚精胺也敏感（在6 mM亚精胺存在下为对照的20%）。腐胺和亚精胺的混合物完全消除了赖氨酸脱羧酶活性。这为一种生物合成酶的存在提供了证据，并提出了一种机制来解释在多胺缺乏的细胞中尸胺的出现。
