Astrachan L, Miller J F
J Virol. 1973 May;11(5):792-8. doi: 10.1128/JVI.11.5.792-798.1973.
Cadaverine was found in bacteriophage T4 when the host cells of Escherichia coli K-12 were grown in complex media and aerated by agitation. Only traces of cadaverine were found if the host was grown and agitated in synthetic medium or was aerated by vigorous bubbling in a complex medium. When the host cells were grown anaerobically in a complex medium, cadaverine became the major polyamine in the progeny phage. The polyamine content comprised 80% cadaverine, 14% spermidine (or its recently discovered homologue, N-3-aminopropyl-1, 5-diaminopentane), and the remainder putrescine. The conditions that favored appearance of cadaverine are known to be required for induction of lysine decarboxylase. It was shown that lysine was the sole source of bacterial cadaverine.
当大肠杆菌K-12的宿主细胞在复合培养基中生长并通过搅拌通气时，在噬菌体T4中发现了尸胺。如果宿主在合成培养基中生长并搅拌，或者在复合培养基中通过剧烈鼓泡通气，则仅发现痕量的尸胺。当宿主细胞在复合培养基中厌氧生长时，尸胺成为子代噬菌体中的主要多胺。多胺含量包括80%的尸胺、14%的亚精胺（或其最近发现的同系物N-3-氨丙基-1,5-二氨基戊烷），其余为腐胺。已知诱导赖氨酸脱羧酶需要有利于尸胺出现的条件。结果表明，赖氨酸是细菌尸胺的唯一来源。
