Haffar A A, Fuselier P A, Baker C J
J Clin Microbiol. 1983 Jul;18(1):101-3. doi: 10.1128/jcm.18.1.101-103.1983.
At our hospital (Jefferson Davis Hospital, Houston, Tex.) since 1979, non-group D alpha-hemolytic streptococci have been isolated with increasing frequency from neonatal blood cultures with clinical findings of sepsis. A total of 47 such isolates were identified to the species level by the scheme of Facklam and were compared with 57 genital isolates from 167 maternity patients. Among the genital isolates, S. sanguis II and S. MG-intermedius accounted for 53 and 28%, respectively, and both were significantly less common in neonatal cultures (23 and 11%, respectively; P less than 0.05). Among neonatal isolates, S. mitis was the single most frequent species (35%), in contrast to its rare occurrence in maternal cultures (3.4%; P less than 0.001). The disparity between the prevalence of S. mitis in neonatal compared with maternal cultures suggests that this species of non-group D alpha-hemolytic streptococci may have increased virulence in neonatal hosts.
自1979年以来，在我们医院（得克萨斯州休斯敦市杰斐逊·戴维斯医院），从伴有败血症临床表现的新生儿血培养物中分离出非D群α溶血性链球菌的频率不断增加。按照法克拉姆的方案，共鉴定出47株此类菌株至种水平，并与167例产妇的57株生殖道分离株进行了比较。在生殖道分离株中，血链球菌II型和中间型米勒链球菌分别占53%和28%，而在新生儿培养物中均明显较少见（分别为23%和11%；P<0.05）。在新生儿分离株中，缓症链球菌是最常见的单一菌种（35%），而在产妇培养物中很少出现（3.4%；P<0.001）。与产妇培养物相比，缓症链球菌在新生儿培养物中的流行率差异表明，这种非D群α溶血性链球菌在新生儿宿主中可能具有增强的毒力。
