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甲状腺内分泌病理学、产科发病率与精神分裂症:对一百个有精神分裂症先证者的家庭的调查。

Thryo-endocrine pathology, obstetric morbidity and schizophrenia: survey of a hundred families with a schizophrenic proband.

作者信息

MacSweeney D, Timms P, Johnson A

出版信息

Psychol Med. 1978 Feb;8(1):151-5. doi: 10.1017/s0033291700006735.

DOI:10.1017/s0033291700006735
PMID:635067
Abstract

This preliminary communication reports that the mothers of 104 schizophrenic patients had: (1) a significantly higher incidence of thyroid disease than a carefully matched control group; (2) significantly more abortions, still-births and greater infant mortality. The findings and possible relevance of thyroid disease to schizophrenia are discussed. Three prospective studies currently in progress are outlined.

摘要

这篇初步通讯报道,104名精神分裂症患者的母亲有:(1)甲状腺疾病的发病率显著高于精心匹配的对照组;(2)流产、死产显著更多,婴儿死亡率更高。本文讨论了这些发现以及甲状腺疾病与精神分裂症可能的相关性。概述了目前正在进行的三项前瞻性研究。

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Thryo-endocrine pathology, obstetric morbidity and schizophrenia: survey of a hundred families with a schizophrenic proband.甲状腺内分泌病理学、产科发病率与精神分裂症:对一百个有精神分裂症先证者的家庭的调查。
Psychol Med. 1978 Feb;8(1):151-5. doi: 10.1017/s0033291700006735.
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Congenital hypothyroidism and hyperthyroidism in monozygotic twin girls.单卵双胞胎女孩的先天性甲状腺功能减退症和甲状腺功能亢进症。
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引用本文的文献

1
Hypothyroxinemia During Gestation and Offspring Schizophrenia in a National Birth Cohort.全国出生队列中孕期甲状腺素水平低下与子代精神分裂症
Biol Psychiatry. 2016 Jun 15;79(12):962-70. doi: 10.1016/j.biopsych.2015.06.014. Epub 2015 Jun 19.
2
Thyroid function in different psychiatric disorders.不同精神障碍中的甲状腺功能。
Indian J Psychiatry. 1980 Apr;22(2):200-2.
3
Factors involved in the rate of fall of thyroid stimulating hormone in treated hypothyroidism.治疗后甲状腺功能减退症中促甲状腺激素下降速率的相关因素。
Arch Dis Child. 1997 Dec;77(6):526-7. doi: 10.1136/adc.77.6.526.
4
Circumscribed malformation and nerve cell alterations in the entorhinal cortex of schizophrenics. Pathogenetic and clinical aspects.
J Neural Transm Gen Sect. 1994;98(2):83-106. doi: 10.1007/BF01277013.