Pinegin B V, Korshunov V M, Ivanova N P, Chakhava O V, Shustrova N M
Zh Mikrobiol Epidemiol Immunobiol. 1983 Jun(6):41-6.
Antibiotic-resistant bifidobacteria have the ability to actively interact with mucosal tissue from the intestine of mice and rats in vitro and to adapt well in the intestinal tract of normal and germ-free rats, when introduced both with and without antibiotics; in some cases antibiotics enhance the ability of bifidobacteria to adapt in the intestine. The interaction between antibiotic-resistant bifidobacteria and mucosal tissue from the intestine remains unaffected by the prolonged action of 0.1M SDS and Tween-80 solutions, 0.1% trypsin and hyaluronidase. Antibiotic-resistant bifidobacteria introduced into the intestinal tract of rats in combination with gentamycin effectively inhibit the multiplication of exogenous enterobacteria infecting the digestive tract after the cessation of the antibiotic administration.
具有抗生素抗性的双歧杆菌能够在体外与小鼠和大鼠肠道的黏膜组织积极相互作用，并且在有无抗生素的情况下引入正常和无菌大鼠的肠道后都能很好地适应；在某些情况下，抗生素会增强双歧杆菌在肠道中的适应能力。具有抗生素抗性的双歧杆菌与肠道黏膜组织之间的相互作用不受0.1M SDS和吐温80溶液、0.1%胰蛋白酶和透明质酸酶长时间作用的影响。与庆大霉素联合引入大鼠肠道的具有抗生素抗性的双歧杆菌在停止施用抗生素后能有效抑制感染消化道的外源肠道细菌的繁殖。
