Bordelon J Y, Legrand P, Gewin W C, Sanders C V
Am Rev Respir Dis. 1983 Sep;128(3):465-8. doi: 10.1164/arrd.1983.128.3.465.
The results of bacterial cultures from transtracheal aspiration and from aspirations obtained by a new telescoping plugged catheter were compared in specimens taken from 13 patients with suspected anaerobic infections of the lower respiratory tract. When all bacterial isolates (potential aerobic pathogens, aerobic nonpathogens, and anaerobes) were counted with transtracheal aspiration as the standard method for comparison, cultures of material obtained by the telescoping plugged catheter technique yielded 22 false negatives and 14 false positives. The results of the 2 methods were in complete agreement in only 3 paired specimens cultured aerobically and in only 6 paired specimens cultured anaerobically. When only potential aerobic pathogens and anaerobes were considered with transtracheal aspiration as the standard method for comparison, cultures of material obtained by the telescoping plugged catheter technique yielded 11 false negatives and 7 false positives, and the results of the 2 methods were in complete agreement in 9 paired specimens cultured aerobically and 6 paired specimens cultured anaerobically. Our results suggest that fiberoptic bronchoscopy using the telescoping plugged catheter technique may be an acceptable method for collecting specimens from the lower respiratory tract, but further studies comparing this method with transtracheal aspiration are needed.
对13例疑似下呼吸道厌氧菌感染患者的标本，比较经气管穿刺吸引与一种新型可伸缩堵塞导管抽吸所获标本的细菌培养结果。以经气管穿刺吸引作为标准比较方法来统计所有细菌分离株（潜在需氧病原体、需氧非病原体和厌氧菌）时，采用可伸缩堵塞导管技术获取的标本培养结果出现22例假阴性和14例假阳性。两种方法的结果仅在3对需氧培养的配对标本以及6对厌氧培养的配对标本中完全一致。以经气管穿刺吸引作为标准比较方法，仅考虑潜在需氧病原体和厌氧菌时，采用可伸缩堵塞导管技术获取的标本培养结果出现11例假阴性和7例假阳性，两种方法的结果在9对需氧培养的配对标本以及6对厌氧培养的配对标本中完全一致。我们的结果表明，使用可伸缩堵塞导管技术的纤维支气管镜检查可能是一种可接受的下呼吸道标本采集方法，但需要进一步研究将该方法与经气管穿刺吸引进行比较。
