Jaffe L F
Dev Biol. 1983 Oct;99(2):265-76. doi: 10.1016/0012-1606(83)90276-2.
A careful reanalysis of the literature indicates that the initial mechanism of activation in sea urchin eggs is remarkably similar to the mechanism established in medaka eggs: i.e., sea urchin eggs are activated by a qualitatively and quantitatively similar calcium explosion; one which is propagated in a wave sustained by the calcium-stimulated release of calcium from internal sources. These sources are probably in the endoplasmic reticulum. An exhaustive survey of the literature reveals that a wide variety of other activating eggs in the vertebrate line also exhibit secretory waves which are propagated at about 10 microns/sec, and can thus be assumed to reflect the same basic mechanism. Activating protostome eggs on the other hand do not exhibit such waves. This and other systematic differences from deuterostomes suggest that unlike deuterostome eggs, protostome eggs are primarily activated by calcium ions which enter the cytosol from the medium, and do so in response to depolarization of the egg's plasma membrane.
对文献的仔细重新分析表明，海胆卵激活的初始机制与青鳉卵中确立的机制非常相似：即海胆卵通过性质和数量上相似的钙爆发来激活；这种钙爆发以由钙刺激从内部来源释放钙所维持的波的形式传播。这些来源可能在内质网中。对文献的详尽调查显示，脊椎动物谱系中各种各样的其他激活卵也表现出以约10微米/秒传播的分泌波，因此可以假定反映了相同的基本机制。另一方面，激活原口动物卵不会表现出这样的波。这种与后口动物的系统差异及其他差异表明，与后口动物卵不同，原口动物卵主要由从介质进入细胞质的钙离子激活，并且是响应于卵质膜的去极化而这样做。
