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大肠杆菌H-10407中两个编码热稳定肠毒素的基因的质粒关联及核苷酸序列关系

Plasmid association and nucleotide sequence relationships of two genes encoding heat-stable enterotoxin production in Escherichia coli H-10407.

作者信息

Moseley S L, Samadpour-Motalebi M, Falkow S

出版信息

J Bacteriol. 1983 Oct;156(1):441-3. doi: 10.1128/jb.156.1.441-443.1983.

DOI:10.1128/jb.156.1.441-443.1983
PMID:6352687
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC215104/
Abstract

Plasmid DNA from enterotoxigenic Escherichia coli strains H-10407 and H-10407-P was examined for nucleotide sequence homology to two E. coli genes encoding infant mouse-active heat-stable enterotoxins (ST). A 62-megadalton plasmid of strain H-10407 contained sequences homologous to the gene encoding a toxin designated STIb, previously isolated from a human isolate of E. coli. A 42-megadalton plasmid of strains H-10407 and H-10407-P contained sequences homologous to the gene encoding a toxin designated STIa, previously isolated from bovine and porcine isolates of E. coli.

摘要

检测了产肠毒素大肠杆菌菌株H - 10407和H - 10407 - P的质粒DNA与两个编码对幼鼠有活性的热稳定肠毒素(ST)的大肠杆菌基因的核苷酸序列同源性。菌株H - 10407的一个62兆道尔顿质粒含有与编码一种名为STIb毒素的基因同源的序列,该毒素先前从一株人源大肠杆菌分离株中分离得到。菌株H - 10407和H - 10407 - P的一个42兆道尔顿质粒含有与编码一种名为STIa毒素的基因同源的序列,该毒素先前从牛源和猪源大肠杆菌分离株中分离得到。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd71/215104/6235f6aa5e15/jbacter00239-0452-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd71/215104/6235f6aa5e15/jbacter00239-0452-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd71/215104/6235f6aa5e15/jbacter00239-0452-a.jpg

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