Pennington C R, Ross P E, Bouchier I A
Scand J Gastroenterol. 1978;13(1):77-80. doi: 10.3109/00365527809179809.
Total and individual serum bile acid concentrations were studied in 18 patients with viral hepatitis. The initial high values returned to the normal range at approximately the same time as the conventional liver function tests. Chenodeoxycholic acid was the predominant bile acid initially, but cholic acid predominated as the disease resolved. All patients had proportionately less doexycholic acid than controls. It is concluded that the measurement of serum bile acid does not provide added information of value in the management of patients with viral hepatitis.
对18例病毒性肝炎患者的血清总胆汁酸浓度和个体胆汁酸浓度进行了研究。最初的高值在与传统肝功能检查大致相同的时间恢复到正常范围。鹅去氧胆酸最初是主要的胆汁酸,但随着疾病的缓解,胆酸占主导地位。所有患者的脱氧胆酸比例均低于对照组。得出的结论是,血清胆汁酸的测定在病毒性肝炎患者的管理中并未提供额外的有价值信息。