Wyklicky H, Skopec M
Infect Control. 1983 Sep-Oct;4(5):367-70. doi: 10.1017/s0195941700059762.
Although by 1931 I. Ph. Semmelweis' achievements and the tragedy of his life had been given their due place in the history of mankind, Alexander Fränkel, formerly Theodor Billroth's assistant and later his biographer, critically stated that the discoverer of the causes of puerperal fever should have defended his discovery with facts rather than with fanaticism. It was only a few years after Semmelweis' death, for instance, that Billroth made laborious experiments. Billroth's work on Coccobacteria had important implications and even influenced Robert Koch, although his hypotheses did not really predict the pathogenic and specific nature of microbes. In 1847 Semmelweis postulated his theory; ie, that the pathological-anatomical changes which he observed in the bodies of the women who died in childbed, in their newborn infants, and in the autopsy findings on his friend Jakob Kolletschka were an entity, morphologically and clinically. He summed them up under the concept of pyemia. Even though Semmelweis was continually abhorred by the evident statistics and would have been able to prove his discovery through animal experiments, he primarily took to the pen to defend his opinion vehemently. Only the clinical facts proved him right during his lifetime; the triumph of bacteriology which began after his death made him not only the "savior of mothers" but also a genial ancestor of bacteriology.
尽管到1931年时,伊格纳兹·塞麦尔维斯的成就和他一生的悲剧在人类历史中已获得应有的地位,但亚历山大·弗兰克尔——他曾是特奥多尔·比尔罗特的助手,后来成为其传记作者——批判性地指出,产褥热病因的发现者本应用事实而非狂热来捍卫自己的发现。例如,就在塞麦尔维斯去世几年后,比尔罗特进行了艰苦的实验。比尔罗特关于球菌的研究具有重要意义,甚至影响了罗伯特·科赫,尽管他的假说是并未真正预测出微生物的致病性和特异性本质。1847年,塞麦尔维斯提出了他的理论,即他在死于产褥期的女性尸体、她们的新生儿以及他的朋友雅各布·科莱奇卡的尸检结果中观察到的病理解剖变化,在形态学和临床上是一个实体。他将这些变化归纳在脓毒症的概念之下。尽管塞麦尔维斯一直为明显的统计数据所憎恶,并且本可以通过动物实验来证明他的发现,但他主要还是拿起笔来激烈地捍卫自己的观点。在他有生之年,只有临床事实证明他是正确的;他死后开始的细菌学的胜利,不仅使他成为“母亲们的救星”,也使他成为细菌学的一位天才先驱。