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相似文献

1
Nuclear RNA-protein interactions and messenger RNA processing.核RNA-蛋白质相互作用与信使RNA加工
J Cell Biol. 1983 Nov;97(5 Pt 1):1321-6. doi: 10.1083/jcb.97.5.1321.
2
Heat shock alters nuclear ribonucleoprotein assembly in Drosophila cells.热休克改变果蝇细胞中的核糖核蛋白组装。
Mol Cell Biol. 1983 Feb;3(2):161-71. doi: 10.1128/mcb.3.2.161-171.1983.
3
Messenger RNA processing and nuclear structure: isolation of nuclear ribonucleoprotein particles containing beta-globin messenger RNA precursors.信使核糖核酸加工与核结构：含β-珠蛋白信使核糖核酸前体的核糖核蛋白颗粒的分离
J Cell Biol. 1980 Oct;87(1):47-54. doi: 10.1083/jcb.87.1.47.
4
Independent deposition of heterogeneous nuclear ribonucleoproteins and small nuclear ribonucleoprotein particles at sites of transcription.异质性核糖核蛋白和小核核糖核蛋白颗粒在转录位点的独立沉积。
Proc Natl Acad Sci U S A. 1992 Sep 15;89(18):8409-13. doi: 10.1073/pnas.89.18.8409.
5
Synergistic stimulation of HIV-1 rev-dependent export of unspliced mRNA to the cytoplasm by hnRNP A1.异质性核糖核蛋白A1对HIV-1依赖于Rev的未剪接mRNA向细胞质输出的协同刺激作用。
J Mol Biol. 1999 Feb 5;285(5):1951-64. doi: 10.1006/jmbi.1998.2473.
6
The hnRNP F protein: unique primary structure, nucleic acid-binding properties, and subcellular localization.异质性核糖核蛋白F蛋白：独特的一级结构、核酸结合特性及亚细胞定位。
Nucleic Acids Res. 1994 Mar 25;22(6):1059-67. doi: 10.1093/nar/22.6.1059.
7
Analysis of RNA-protein interactions of mouse liver cytochrome P4502A5 mRNA.小鼠肝脏细胞色素P4502A5 mRNA的RNA-蛋白质相互作用分析
Biochem J. 1999 May 1;339 ( Pt 3)(Pt 3):695-703.
8
AU-A, an RNA-binding activity distinct from hnRNP A1, is selective for AUUUA repeats and shuttles between the nucleus and the cytoplasm.AU-A是一种与hnRNP A1不同的RNA结合活性蛋白，对AUUUA重复序列具有选择性，并在细胞核和细胞质之间穿梭。
Nucleic Acids Res. 1994 Jan 25;22(2):238-46. doi: 10.1093/nar/22.2.238.
9
Presence of the pre-mRNA for the 72k DNA binding protein in hnRNP from early adenovirus-2 infected HeLa cells.
Biochem Biophys Res Commun. 1982 Mar 30;105(2):603-9. doi: 10.1016/0006-291x(82)91477-2.
10
In vivo splicing of the premRNAs from early region 3 of adenovirus-2: association of precursors, intermediates and products with hnRNP.腺病毒2型早期区域3前体mRNA的体内剪接：前体、中间体和产物与核不均一核糖核蛋白的关联
Nucleic Acids Res. 1986 May 27;14(10):4171-85. doi: 10.1093/nar/14.10.4171.

引用本文的文献

1
RNA-dependent phosphorylation of a nuclear RNA binding protein.一种核RNA结合蛋白的RNA依赖性磷酸化作用
Proc Natl Acad Sci U S A. 1997 Feb 18;94(4):1064-8. doi: 10.1073/pnas.94.4.1064.
2
Serine/threonine phosphorylation regulates binding of C hnRNP proteins to pre-mRNA.丝氨酸/苏氨酸磷酸化调节核不均一核糖核蛋白（hnRNP）与前体信使核糖核酸（pre-mRNA）的结合。
Proc Natl Acad Sci U S A. 1993 Aug 15;90(16):7764-8. doi: 10.1073/pnas.90.16.7764.
3
A major heat-shock protein defined by a monoclonal antibody.一种由单克隆抗体定义的主要热休克蛋白。
EMBO J. 1984 Aug;3(8):1871-9. doi: 10.1002/j.1460-2075.1984.tb02061.x.
4
Isolation and characterization of the RNA2+, RNA4+, and RNA11+ genes of Saccharomyces cerevisiae.酿酒酵母RNA2 +、RNA4 +和RNA11 +基因的分离与鉴定
J Bacteriol. 1984 Dec;160(3):1093-100. doi: 10.1128/jb.160.3.1093-1100.1984.
5
Interactions of U1 RNP with heterogeneous nuclear RNA in rat Novikoff hepatoma nuclei.大鼠诺维科夫肝癌细胞核中U1核糖核蛋白与不均一核RNA的相互作用。
Mol Cell Biochem. 1984 Nov;65(1):45-55. doi: 10.1007/BF00226018.
6
General organization of protein in HeLa 40S nuclear ribonucleoprotein particles.HeLa 40S核糖核蛋白颗粒中蛋白质的总体组织
J Cell Biol. 1985 May;100(5):1570-81. doi: 10.1083/jcb.100.5.1570.
7
Single stranded DNA binding proteins derive from hnRNP proteins by proteolysis in mammalian cells.在哺乳动物细胞中，单链DNA结合蛋白通过蛋白水解作用从核不均一核糖核蛋白（hnRNP）衍生而来。
Nucleic Acids Res. 1985 Sep 25;13(18):6577-90. doi: 10.1093/nar/13.18.6577.
8
Injected anti-sense RNAs specifically block messenger RNA translation in vivo.注射的反义RNA在体内特异性地阻断信使RNA的翻译。
Proc Natl Acad Sci U S A. 1985 Jan;82(1):144-8. doi: 10.1073/pnas.82.1.144.
9
Identification of proteins that bind tightly to pre-mRNA during in vitro splicing.在体外剪接过程中紧密结合前体mRNA的蛋白质的鉴定。
Proc Natl Acad Sci U S A. 1986 Jun;83(11):3718-22. doi: 10.1073/pnas.83.11.3718.
10
Ribonucleoproteins package 700 nucleotides of pre-mRNA into a repeating array of regular particles.核糖核蛋白将700个核苷酸的前体mRNA包装成规则颗粒的重复阵列。
Mol Cell Biol. 1988 Jul;8(7):2884-95. doi: 10.1128/mcb.8.7.2884-2895.1988.

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CIRCULATING INTERFERON AFTER MEASLES VACCINATION.麻疹疫苗接种后的循环干扰素
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Varying patterns of protein synthesis in Drosophila during heat shock: implications for regulation.果蝇在热休克期间蛋白质合成的不同模式：对调控的影响
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Ribonucleoprotein organization of eukaryotic RNA. XV. Different nucleoprotein structures of globin messenger RNA sequences in nuclear and polyribosomal ribonucleoprotein particles.真核生物RNA的核糖核蛋白组织。十五。核内和多核糖体核糖核蛋白颗粒中珠蛋白信使RNA序列的不同核蛋白结构。
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核RNA-蛋白质相互作用与信使RNA加工

Nuclear RNA-protein interactions and messenger RNA processing.

作者信息

Pederson T

出版信息

J Cell Biol. 1983 Nov;97(5 Pt 1):1321-6. doi: 10.1083/jcb.97.5.1321.

DOI:10.1083/jcb.97.5.1321
PMID:6355116
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2112690/
Abstract

Eucaryotic messenger RNA precursors are processed in nuclear ribonucleoprotein particles (hnRNP). Here recent work on the structure of hnRNP is reviewed, with emphasis on function. Detailed analysis of a specific case, the altered assembly of hnRNP in heat-shocked Drosophila and mammalian cells, leads to a general hypothesis linking hnRNP structure and messenger RNA processing.

摘要

真核生物信使核糖核酸前体在核糖核蛋白颗粒（hnRNP）中进行加工。本文综述了hnRNP结构的近期研究工作，重点是其功能。对一个特定案例——热休克果蝇和哺乳动物细胞中hnRNP组装改变的详细分析，得出了一个将hnRNP结构与信使核糖核酸加工联系起来的一般性假说。