核RNA-蛋白质相互作用与信使RNA加工
Nuclear RNA-protein interactions and messenger RNA processing.
作者信息
Pederson T
出版信息
J Cell Biol. 1983 Nov;97(5 Pt 1):1321-6. doi: 10.1083/jcb.97.5.1321.
Abstract
Eucaryotic messenger RNA precursors are processed in nuclear ribonucleoprotein particles (hnRNP). Here recent work on the structure of hnRNP is reviewed, with emphasis on function. Detailed analysis of a specific case, the altered assembly of hnRNP in heat-shocked Drosophila and mammalian cells, leads to a general hypothesis linking hnRNP structure and messenger RNA processing.
摘要
真核生物信使核糖核酸前体在核糖核蛋白颗粒（hnRNP）中进行加工。本文综述了hnRNP结构的近期研究工作，重点是其功能。对一个特定案例——热休克果蝇和哺乳动物细胞中hnRNP组装改变的详细分析，得出了一个将hnRNP结构与信使核糖核酸加工联系起来的一般性假说。
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