Cabello G, Levieux D, Girardeau J P, Lefaivre J
Res Vet Sci. 1983 Sep;35(2):242-4.
Continuous infusion of thyroid hormones during the last 12 days of gestation in ovine fetuses was associated with: a reduction of the rate of appearance of blood IgG1 after colostrum feeding in the newborn lambs; an important reduction of the number of jejunal cells filled with IgG1, 12 hours post partum, suggesting a premature closure of the intestinal permeability to IgG1; and a significant reduction of the K99+ Escherichia coli adhesion on the intestinal villi. These results could partly explain relationships observed previously between perinatal thyroid function abnormalities and the occurrence of neonatal diseases.
在绵羊胎儿妊娠的最后12天持续输注甲状腺激素与以下情况相关：新生羔羊初乳喂养后血液中IgG1出现速率降低；产后12小时空肠中充满IgG1的细胞数量显著减少，提示肠道对IgG1的通透性过早关闭；以及肠道绒毛上K99 +大肠杆菌黏附显著减少。这些结果可以部分解释先前观察到的围产期甲状腺功能异常与新生儿疾病发生之间的关系。
