Cabello G, Levieux D
Res Vet Sci. 1981 Sep;31(2):190-4.
The relationships between the length of gestation, the birthweight, thyroid and adrenocortical function, and the absorption of colostral IgG1 were studied in 18 Romanov lambs born spontaneously between 135 and 145 days of gestation. All the lambs were bottle-fed in accurately standardised conditions with a bovine colostrum pool. Negative relationships were observed between the maximum plasma IgG1 levels and the length of gestation, the birthweight, or the plasma thyreostimulin levels near birth and between the times at which the maximum plasma IgG1 levels occurred and the length of gestation, or the plasma thyroxine levels near birth. The half-lives of bovine IgG1 in the plasma of the lambs were also related to the plasma thyroxine level at birth. These results suggest that maturity of the newborn lamb, assessed by the length of gestation and the hormonal status, could greatly influence the acquisition and maintenance of colostral immunity.
对18只在妊娠135至145天之间自然出生的罗曼诺夫羔羊，研究了妊娠期长度、出生体重、甲状腺和肾上腺皮质功能以及初乳IgG1吸收之间的关系。所有羔羊在精确标准化条件下用牛初乳池进行奶瓶喂养。观察到最大血浆IgG1水平与妊娠期长度、出生体重或出生时血浆促甲状腺素水平之间呈负相关，以及最大血浆IgG1水平出现的时间与妊娠期长度或出生时血浆甲状腺素水平之间呈负相关。牛IgG1在羔羊血浆中的半衰期也与出生时的血浆甲状腺素水平有关。这些结果表明，通过妊娠期长度和激素状态评估的新生羔羊成熟度可能会极大地影响初乳免疫的获得和维持。
