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[博伊德4型痢疾的传播趋势及其临床症状特点和病原体生物学特性]

[Trends in the spread of Boyd 4 dysentery and the characteristics of its clinical picture and of the biology of its causative agent].

作者信息

Priamukhina N S, Mashilov V P, Kamyshleev A A, Klimanov A I, Givental' N I

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1983 Aug(8):74-9.

PMID:6356722
Abstract

The data on the proportion of S. boydii 4 in the general structure of the causative agents of dysentery, as well as in the intraspecific structure of S. boydii, in some areas of the USSR in 1977-1981 are presented. S. boydii strains 4, circulating in one of the areas where their proportion considerably increased in 1980-1981, corresponded to their taxonomic position in their biological properties, while forming a single biochemical variant according to the character of the fermentation of sorbitol, maltose and arabinose. These strains gave identical antibiotic sensitivity charts and showed pronounced multiple resistance to antibiotics, including ampicillin. The clinical features of the diseases caused by S. boydii 4 consisted in the sharply defined prodromal period and pronounced systemic toxicosis at the initial period of the disease, accompanied by the syndrome of moderate colitis localized mainly on the right side.

摘要

本文给出了1977 - 1981年苏联部分地区痢疾病原体总体结构中以及博伊德氏志贺氏菌种内结构中博伊德氏志贺氏菌4型所占比例的数据。1980 - 1981年在其中一个地区流行且所占比例大幅增加的博伊德氏志贺氏菌4型菌株,在生物学特性上与其分类地位相符,同时根据山梨醇、麦芽糖和阿拉伯糖的发酵特性形成单一生化变种。这些菌株的抗生素敏感性图谱相同,且对包括氨苄青霉素在内的抗生素表现出明显的多重耐药性。由博伊德氏志贺氏菌4型引起的疾病临床特征为前驱期明确,疾病初期有明显的全身中毒症状,并伴有主要局限于右侧的中度结肠炎综合征。

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