Andersen J T, Bradley W E, Bourne R B
J Urol. 1976 Dec;116(6):786-9. doi: 10.1016/s0022-5347(17)59012-6.
Detrusor and urethral function was studied in 10 patients before and 3 months after transurethral resection of the prostate by means of flowmetry, and simultaneous gas cystometry and integrated sphincter electromyography. THE PATIENTas cystometry and integrated sphincter electromyography. The patient had no clinical signs of neurological disease. Six had neurogenic exaggeration of the detrusor reflex in the preoperative studies. In 3 patients changes in the detrusor reflex were found postoperatively. Postural changes in detrusor reflex excitability were encountered preoperatively and postoperatively. The preoperative finding of detrusor hyperreflexia in the majority of the patients is ascribed to lesions in the detrusor reflex organization at 2 anatomical sites: 1) a subclinical lesion of the cerebral circuits of the detrusor reflex control owing to arteriosclerosis and 2) an increase of sensory detrusor-reflex triggering stimuli from the morphologically changed prostatic urethra. The study calls for diagnostic techniques for delineation of minimal cerebrospinal impairment and objective assessment of the sensory innervation of the urethra.
通过尿流率测定、同步膀胱测压和括约肌肌电图，对10例患者经尿道前列腺切除术前及术后3个月的逼尿肌和尿道功能进行了研究。患者无神经疾病的临床体征。术前研究中有6例存在逼尿肌反射的神经源性亢进。术后在3例患者中发现了逼尿肌反射的变化。术前和术后均出现了逼尿肌反射兴奋性的体位变化。大多数患者术前逼尿肌反射亢进的发现归因于逼尿肌反射组织在两个解剖部位的病变：1）由于动脉硬化导致逼尿肌反射控制脑回路的亚临床病变；2）形态改变的前列腺尿道传入的逼尿肌反射触发刺激增加。该研究需要用于明确最小脑脊髓损伤的诊断技术以及对尿道感觉神经支配进行客观评估。
