Andersen J T, Bradley E W
Br J Urol. 1976 Dec;48(6):493-7. doi: 10.1111/j.1464-410x.1976.tb06689.x.
Assessment of bladder and urethral function in 9 patients with prostatic hypertrophy before and after transurethral resection of the prostate was performed utilising gas cystometry, detrusor reflex activating procedures, combined electromyographic and gas urethral pressure profilometry and uroflowmetry. A high incidence of detrusor hyperreflexia was found preoperatively indicating neurogenic dysfunction of the bladder. Removal of the obstructive tissue implied a change in detrusor reflex function in a part of the patients confirming the findings from a larger series studied with watercytsometry. Decompression or injury of sensory nerve endings in the prostatic urethra thus seem to determine detrusor function after surgery to the prostate. The impact of the resection upon urethral function was an increase in maximum urinary flow due to a significant shortening of the functional urethral length. No change in maximum urethral intramural pressure could be demonstrated.
利用气体膀胱测压法、逼尿肌反射激活程序、联合肌电图和气体尿道压力测定法以及尿流率测定法，对9例前列腺肥大患者经尿道前列腺切除术前和术后的膀胱和尿道功能进行了评估。术前发现逼尿肌反射亢进的发生率很高，提示膀胱存在神经源性功能障碍。切除梗阻组织意味着部分患者的逼尿肌反射功能发生改变，这证实了用液体膀胱测压法研究的更大系列的结果。因此，前列腺尿道感觉神经末梢的减压或损伤似乎决定了前列腺手术后的逼尿肌功能。切除术对尿道功能的影响是最大尿流增加，这是由于功能性尿道长度显著缩短所致。最大尿道壁内压未见变化。
