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针对人骨髓单核细胞分化抗原的单克隆抗体。

Monoclonal antibodies specific for differentiation antigens of human myelomonocytic cells.

作者信息

Perussia B

出版信息

Biomed Pharmacother. 1983;37(3):113-8.

PMID:6357302
Abstract

Several monoclonal antibodies specific for human cells of the myelomonocytic lineage at discrete stages of differentiation have been described. In this review I briefly summarize the results obtained with these reagents and discuss their possible use for the study of cell lineage and functional activities of normal peripheral blood leukocytes, for the analysis of myelomonocytic cell differentiation in vivo and in vitro and for the antigenic phenotyping of leukemia cells.

摘要

已经描述了几种针对髓单核细胞系人类细胞在不同分化阶段的特异性单克隆抗体。在这篇综述中,我简要总结了使用这些试剂所获得的结果,并讨论了它们在研究正常外周血白细胞的细胞谱系和功能活性、分析体内和体外髓单核细胞分化以及白血病细胞的抗原表型分析方面的可能用途。

相似文献

1
Monoclonal antibodies specific for differentiation antigens of human myelomonocytic cells.针对人骨髓单核细胞分化抗原的单克隆抗体。
Biomed Pharmacother. 1983;37(3):113-8.
2
Monoclonal antibodies (series Bra-) of broad (non-lineage) or restricted (myelomonocytic) reactivities elicited with granulocytes or K 562 cells.用粒细胞或K562细胞引发的具有广泛(非谱系)或受限(髓单核细胞)反应性的单克隆抗体(Bra-系列)
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3
Normal and malignant human myelocytic and monocytic cells identified by monoclonal antibodies.通过单克隆抗体鉴定的正常和恶性人类髓细胞和单核细胞
J Immunol. 1982 Feb;128(2):876-81.
4
Biochemistry and expression of myelomonocytic antigens.骨髓单核细胞抗原的生物化学与表达
J Immunol. 1986 Dec 15;137(12):3909-14.
5
Antigens on human monocytes identified by monoclonal antibodies.通过单克隆抗体鉴定的人类单核细胞上的抗原。
J Immunol. 1981 Apr;126(4):1435-42.
6
Application of series of monoclonal antibodies against human white cell differentiation antigens and the common ALL antigen in the characterization of leukemia cells.一系列抗人白细胞分化抗原及普通急性淋巴细胞白血病抗原的单克隆抗体在白血病细胞特性鉴定中的应用。
Arch Immunol Ther Exp (Warsz). 1984;32(1):43-9.
7
[Induction of differentiation of human myelomonocytic cell lines by chemical inducers: analysis of surface antigens with monoclonal antibodies].
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8
A human myeloid cell differentiation antigen (C3H6) recognized by a murine monoclonal antibody.一种被鼠单克隆抗体识别的人类髓样细胞分化抗原(C3H6)。
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9
Interferon alpha selectively affects expression of the human myeloid cell nuclear differentiation antigen in late stage cells in the monocytic but not the granulocytic lineage.干扰素α选择性地影响单核细胞系而非粒细胞系晚期细胞中人髓细胞核分化抗原的表达。
J Cell Biochem. 1994 Feb;54(2):198-206. doi: 10.1002/jcb.240540208.
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Differentiation antigens of human hemopoietic cells: patterns of reactivity of two monoclonal antibodies.人造血细胞的分化抗原:两种单克隆抗体的反应模式
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