McKenzie F N, Heimbecker R O, Wall W, Robert A, Black L, Barr R
Surgery. 1978 Apr;83(4):470-5.
Intraoperative autotransfusion was studied in 62 patients undergoing elective or emergency thoracic or abdominal vascular surgery systemic heparinization. The results in 58 patients who received a mean autotransfusion volume of 1.8 liters were compared with a group of four patients in whom 9 liters of blood was autotransfused. The quality of the autotransfused blood also was studied and was shown to have a normal platelet count (mean, 144,000/cu mm) and normal fibrinogen value (mean, 212 mg%). No significant differences in the hematological or coagulation parameters measured were detected in the groups given moderate or massive autotransfusion. The mean homologous blood requirement during the hospital admission in the "moderate" group was 300 ml and in the "massive" group 1,000 ml. With careful technique excessive hemolysis or pulmonary microaggregate embolism does not occur; 75% of patients required no homologous blood throughout their hospital admission. No complications which would be attributed to autotransfusion were seen in either group. It is concluded that intraoperative autotransfusion is safe and effective and deserves wider application.
对62例接受择期或急诊胸腹部血管手术并全身肝素化的患者进行了术中自体输血研究。将58例平均自体输血量为1.8升的患者的结果与4例自体输血量为9升的患者组进行了比较。还对自体输血的血液质量进行了研究，结果显示血小板计数正常（平均144,000/立方毫米），纤维蛋白原值正常（平均212毫克%）。在接受中度或大量自体输血的组中，所测量的血液学或凝血参数没有显著差异。“中度”组患者住院期间平均异体血需求量为300毫升，“大量”组为1000毫升。采用谨慎的技术不会发生过度溶血或肺微聚体栓塞；75%的患者在整个住院期间不需要异体血。两组均未出现可归因于自体输血的并发症。结论是术中自体输血安全有效，值得更广泛应用。
