Fiselier T, Monnens L, Moerman E, Van Munster P, Jansen M, Peer P
Int J Pediatr Nephrol. 1983 Sep;4(3):181-5.
The influence of venepuncture on plasma renin activity (PRA), cortisol, and serum noradrenaline and adrenaline concentration in infants and children was evaluated by comparing values obtained immediately on insertion of an indwelling intravenous line (venepuncture value) and 5 and 60 minutes later. PRA values 5 min after venepuncture in the total group of infants and children were significantly higher (P less than 0.001) than venepuncture values. There was no significant difference between PRA values at 60 min compared to venepuncture or 5 min values. A well performed venepuncture does not systematically affect the PRA values obtained. A significant difference between values for noradrenaline, adrenaline and cortisol at the various points of time could not be demonstrated. The number of lower values for noradrenaline and adrenaline at 60 min, however, prevailed. The stress of a well performed venepuncture is not an explanation for the greater scatter of basal PRA levels in infants and young children.
通过比较留置静脉输液管插入时立即获得的值（静脉穿刺值）以及5分钟和60分钟后的数值，评估静脉穿刺对婴幼儿血浆肾素活性（PRA）、皮质醇以及血清去甲肾上腺素和肾上腺素浓度的影响。婴幼儿总组中，静脉穿刺后5分钟的PRA值显著高于静脉穿刺值（P<0.001）。与静脉穿刺值或5分钟时的值相比，60分钟时的PRA值无显著差异。良好的静脉穿刺操作不会系统性地影响所获得的PRA值。在不同时间点，去甲肾上腺素、肾上腺素和皮质醇的值之间未显示出显著差异。然而，60分钟时去甲肾上腺素和肾上腺素较低值的数量占优势。良好的静脉穿刺应激并不能解释婴幼儿基础PRA水平的更大离散度。
