Shimomura K
Department of Paediatrics, Faculty of Medicine, Kyushu University, Fukuoka.
Fukuoka Igaku Zasshi. 1991 Dec;82(12):671-9.
The levels of plasma renin activity (PRA) and plasma aldosterone concentration (PAC) have been known to increase by the influence of crying in infants and toddlers, but no precise informations are available. We evaluated the changes of PRA and PAC after crying by comparing values obtained from 30 infants and toddlers within one minute after the onset of crying, as induced by venopuncture, and three and five minutes after continuation of crying (PRA1, PRA3, PRA5, and PAC1, PAC3, PAC5). The age of these subjects ranged from one to thirty months (median sixteen months). PRA1, PRA3 and PRA5 were 4.0 +/- 1.8 ng/ml per hour, 5.5 +/- 2.7 ng/ml per hour, 7.8 +/- 4.2 ng/ml per hour, respectively. PAC1, PAC3 and PAC5 were 210 +/- 110 pg/ml, 231 +/- 118 pg/ml, 269 +/- 145 pg/ml, respectively. Both PRA and PAC increased with elapsing time. The increase in PRA was marked after a short episode of crying, but that in PAC was of a mild degree. When to evaluate the levels of PRA and PAC in infants and children, especially that of PRA, one should take into consideration of the conditions of the subject such as the duration of crying at blood sampling.
已知婴幼儿哭泣会使血浆肾素活性（PRA）和血浆醛固酮浓度（PAC）升高，但尚无确切信息。我们通过比较30名婴幼儿在静脉穿刺诱导哭泣开始后1分钟内、哭泣持续3分钟和5分钟后（PRA1、PRA3、PRA5以及PAC1、PAC3、PAC5）获得的值，评估哭泣后PRA和PAC的变化。这些受试者的年龄在1至30个月之间（中位数为16个月）。PRA1、PRA3和PRA5分别为每小时4.0±1.8纳克/毫升、每小时5.5±2.7纳克/毫升、每小时7.8±4.2纳克/毫升。PAC1、PAC3和PAC5分别为210±110皮克/毫升、231±118皮克/毫升、269±145皮克/毫升。PRA和PAC均随时间推移而升高。短时间哭泣后PRA升高明显，但PAC升高程度较轻。在评估婴幼儿PRA和PAC水平时，尤其是PRA水平时，应考虑受试者的状况，如采血时的哭泣持续时间。
