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酒精性癫痫:一组病例综述及拟议的分类与病因发病机制

Alcoholic epilepsy: review of a series and proposed classification and etiopathogenesis.

作者信息

Devetag F, Mandich G, Zaiotti G, Toffolo G G

出版信息

Ital J Neurol Sci. 1983 Sep;4(3):275-84. doi: 10.1007/BF02043479.

Abstract

A review of the convulsive seizures of 153 alcoholics is followed by a proposed classification with the aim of defining more precisely the pattern of so-called alcoholic epilepsy and distinguishing it from the other alcohol-related seizures (due to sudden changes in alcohol intake: convulsive inebriation or alcohol withdrawal seizures) and seizures in which alcohol is only one of the pathogenetic factors. Particular attention is devoted to an analysis and comparison of alcohol withdrawal seizures and alcoholic epilepsy, which are a source of nosological confusion. The results of oral glucose tolerance tests suggest an etiopathogenesis for alcoholic epilepsy based on the carbohydrate metabolism.

摘要

对153名酗酒者的惊厥性癫痫发作进行回顾后,提出了一种分类方法,旨在更精确地界定所谓酒精性癫痫的模式,并将其与其他与酒精相关的癫痫发作(由于酒精摄入量突然变化:惊厥性醉酒或酒精戒断性癫痫发作)以及酒精仅是致病因素之一的癫痫发作区分开来。特别关注对酒精戒断性癫痫发作和酒精性癫痫的分析与比较,这两者是病因学混淆的根源。口服葡萄糖耐量试验结果提示基于碳水化合物代谢的酒精性癫痫的病因发病机制。

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