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酒精性癫痫的电生理方面(作者译)

[Electrophysiological aspects of alcoholic epilepsy (author's transl)].

作者信息

Touchon J, Besset A, Baldy-Moulinier M, Billiard M, Uziel A, Passouant P

出版信息

Rev Electroencephalogr Neurophysiol Clin. 1981 Dec;11(3-4):514-9. doi: 10.1016/s0370-4475(81)80094-9.

Abstract

Two types of neurophysiological investigations (standard EEG and polygraphic recording of sleep) were performed on a group of subjects suffering from 'alcoholic epilepsy'. Results were then compared with data from normal subjects and chronic alcoholics without epilepsy. Epileptic patterns on standard EEG are rare. They are increased by sleep. Both the alteration of basal activity in wakefulness and the organization of sleep point to a dysfunction of the CNS. The role of chronic alcoholic intoxication in epileptic seizures could be explained through the slowly decreasing biochemical cerebral action after withdrawal, rather than by a local or diffuse effect in the CNS level.

摘要

对一组患有“酒精性癫痫”的受试者进行了两种神经生理学检查(标准脑电图和睡眠多导记录)。然后将结果与正常受试者和无癫痫的慢性酒精中毒者的数据进行比较。标准脑电图上的癫痫样模式很少见。睡眠会使其增加。清醒时基础活动的改变和睡眠结构均表明中枢神经系统功能障碍。慢性酒精中毒在癫痫发作中的作用可以通过戒断后大脑生化作用的缓慢下降来解释,而不是通过中枢神经系统水平的局部或弥漫性作用来解释。

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