Olsen G J, McCarroll R, Sogin M L
Nucleic Acids Res. 1983 Nov 25;11(22):8037-49. doi: 10.1093/nar/11.22.8037.
We have used comparative analyses of prokaryotic and eukaryotic small subunit ribosomal RNAs to deduce a secondary structure for the Dictyostelium discoideum 18S rRNA. Most of the duplex regions are evolutionarily conserved in all organisms. We have taken advantage of the variation to the D. discoideum sequence (relative to the yeast and frog 19S rRNAs) to identify additional helical regions which are common to the eukaryotic 18S rRNAs.
我们利用原核生物和真核生物小亚基核糖体RNA的比较分析,推断出盘基网柄菌18S rRNA的二级结构。大多数双链区在所有生物中都是进化保守的。我们利用盘基网柄菌序列(相对于酵母和青蛙的19S rRNAs)的变异,来识别真核生物18S rRNAs共有的其他螺旋区域。