Autologous marrow transplantation after karyotypic conversion to normal in blastic phase of chronic myelocytic leukemia.
作者信息
Vogler W R, Winton E F, James S, O'Neill S, Granade S, Mallard G
出版信息
Am J Med. 1983 Dec;75(6):1080-4. doi: 10.1016/0002-9343(83)90893-8.
PMID:6359875
Abstract
A patient with blastic transformation of Philadelphia chromosome-positive chronic myelocytic leukemia was treated with acridinyl anisidide, which resulted in conversion to a normal karyotype. At that time, bone marrow was harvested and cryopreserved. After relapse, the patient was treated with cyclophosphamide and fractionated total body irradiation followed by autologous marrow transplantation. Serial karyotypes and blood counts, determined up to 14 months after transplantation, remained normal.
摘要
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