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经鼻持续气道正压通气可消除打鼾以及阻塞性睡眠呼吸暂停。

Positive nasal airway pressure eliminates snoring as well as obstructive sleep apnea.

作者信息

Berry R B, Block A J

出版信息

Chest. 1984 Jan;85(1):15-20. doi: 10.1378/chest.85.1.15.

Abstract

Nine men who were habitual snorers were studied during a control and a treatment night (in random order) to assess the effect of nasal continuous positive airway pressure (CPAP) on snoring, sleep-disordered breathing, and nocturnal oxygen desaturation. Four subjects had symptoms suggestive of the sleep apnea syndrome, but the other five were asymptomatic. Polysomnography and recordings of snores were obtained on both nights. On the treatment night, the subjects wore a customized infant anesthesia mask over their noses, and CPAP was applied and adjusted upward from 4 cm H2O to a level that obliterated snoring. Nasal CPAP (range 4 to 13 cm H2O) reduced the mean number of snores per night from 1,015 per subject to 23 per subject (p less than 0.01). Mean numbers of episodes of apnea, hypopnea, and desaturation were also significantly reduced. Analysis of sleep structure showed no significant differences in sleep period time, total sleep time, or the percentages of stages 3 and 4 sleep. The percentage of stages 1 and 2 was significantly greater on control nights, and the percentage of REM sleep was greater on treatment nights. On the control nights, snoring was common in stages 3 and 4 and least common during REM sleep.

摘要

对9名习惯性打鼾者在一个对照夜和一个治疗夜(顺序随机)进行了研究,以评估经鼻持续气道正压通气(CPAP)对打鼾、睡眠呼吸紊乱和夜间氧饱和度下降的影响。4名受试者有提示睡眠呼吸暂停综合征的症状,但另外5名无症状。两晚均进行了多导睡眠图检查和鼾声记录。在治疗夜,受试者在鼻子上佩戴定制的婴儿麻醉面罩,应用CPAP并从4 cm H2O向上调整至消除打鼾的水平。经鼻CPAP(范围4至13 cm H2O)使每位受试者每晚的平均打鼾次数从1015次降至23次(p<0.01)。呼吸暂停、呼吸浅慢和饱和度下降发作的平均次数也显著减少。睡眠结构分析显示,睡眠时间、总睡眠时间或3期和4期睡眠百分比无显著差异。1期和2期睡眠百分比在对照夜显著更高,快速眼动睡眠百分比在治疗夜更高。在对照夜,打鼾在3期和4期睡眠中常见,在快速眼动睡眠中最少见。

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