Wolff M, Osborne J W, Hanson A L
Neurotoxicology. 1983 Fall;4(3):201-4.
There is adequate evidence that dental amalgam restorations, during and after placement, results in the release of Hg into the patient's body. Whether the Hg released from amalgam is due to placement procedures, surface abrasion, or later corrosion breakdown, there is evidence that a low level Hg release continues for years. It is generally agreed that if amalgam was introduced today as a restorative material, they would never pass F.D.A. approval. With new and more accurate techniques of measuring Hg levels, especially in tissue and blood, additional studies are necessary to relate blood-Hg levels with dental amalgam restorations. Studies must relate existing restorations as well as the placement of new restorations to body-Hg levels. It is possible that we have accepted a potentially dangerous material as being safe.
有充分证据表明,牙科汞合金修复体在放置期间及放置后会导致汞释放到患者体内。无论汞合金释放的汞是由于放置过程、表面磨损还是后期腐蚀分解,都有证据表明低水平的汞释放会持续数年。人们普遍认为,如果今天将汞合金作为一种修复材料引入,它永远不会获得美国食品药品监督管理局的批准。随着测量汞水平的新技术和更精确技术的出现,尤其是在组织和血液中,有必要进行更多研究,以将血液中的汞水平与牙科汞合金修复体联系起来。研究必须将现有的修复体以及新修复体的放置与体内汞水平联系起来。我们有可能已经接受了一种潜在危险的材料并认为它是安全的。