血液细胞中的汞-元素形态的改变：人类暴露的中毒事件。

Mercury in blood cells-Altered elemental profiles : Toxic events in human exposure.

机构信息

Department of Physical Biology, Gustaf Werner Institute, Uppsala University, Box 531, S-751 21, Uppsala, Sweden.

出版信息

Biol Trace Elem Res. 1987 Apr;12(1):309-21. doi: 10.1007/BF02796688.

Abstract

The study was composed of 27 persons that displayed vague symptoms similar to those of the victims of Minamata and Iraq. Skew distributions of mercury were observed in individual erythrocytes and neutrophil granulocytes when measured by PIXE. Mercury could not be detected in the platelets. The erythrocytes also displayed lowered concentrations of magnesium and zinc, together with increased concentrations of calcium and strontium. The neutrophils displayed decreased concentrations of magnesium and zinc and increased concentrations of calcium, strontium, and iron. The presence of mercury and the altered elemental profiles in the erythrocytes and the neutrophil granulocytes are suggested as early signs of exposure.

摘要

该研究由 27 人组成，他们表现出与水俣病和伊拉克受害者相似的模糊症状。当通过 PIXE 测量时，个体红细胞和中性粒细胞中观察到汞的偏态分布。血小板中检测不到汞。红细胞还显示镁和锌的浓度降低，同时钙和锶的浓度增加。中性粒细胞显示镁和锌的浓度降低，钙、锶和铁的浓度增加。红细胞和中性粒细胞中汞的存在和元素图谱的改变被认为是暴露的早期迹象。