Willkens R F
Pharmacology. 1983;27 Suppl 1:48-54. doi: 10.1159/000137899.
The safety and efficacy of suprofen 200 mg q.i.d. and aspirin 650 mg q.i.d. in the treatment of chronic pain due to osteoarthritis were compared in a double-blind, randomized, parallel group study over a 12-week period. Suprofen was comparable to aspirin in the relief of pain and improvement in activity impairment. Results of ocular examination, laboratory data, and vital signs examinations indicated no clinically significant changes for suprofen. No serious side effects were reported by either group.
在一项为期12周的双盲、随机、平行组研究中，比较了每日四次服用200毫克舒洛芬和每日四次服用650毫克阿司匹林治疗骨关节炎所致慢性疼痛的安全性和有效性。舒洛芬在缓解疼痛和改善活动障碍方面与阿司匹林相当。眼科检查、实验室数据和生命体征检查结果表明，舒洛芬没有临床上的显著变化。两组均未报告严重副作用。
