[实验性鼠疫中生存现象的定量特征]

[Quantitative characteristics of the survival phenomenon in experimental plague].

作者信息

Aparin G P, Vershinina T I

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1983 Nov(11):30-3.

Abstract

The method for the quantitative evaluation of the effect of the survival phenomenon is proposed, which makes it possible to carry out the rapid single-stage determination of the immunogenicity of Pasteurella pestis avirulent strains. The low specificity of the survival phenomenon in plague has been shown. The accumulation of immunogenic avirulent cells in the population of virulent P. pestis has been found to decrease their pathogenic action to a greater extent than the accumulation of nonimmunogenic avirulent cells.

摘要

提出了一种对存活现象效果进行定量评估的方法，该方法使得快速单阶段测定鼠疫耶尔森氏菌无毒菌株的免疫原性成为可能。已证明鼠疫中存活现象的特异性较低。已发现无毒力鼠疫耶尔森氏菌群体中免疫原性无毒细胞的积累比非免疫原性无毒细胞的积累更能在更大程度上降低其致病作用。