快中子辐照与皮下注射四氯化碳或氯仿对C57Bl6小鼠的联合作用。
Combined effects of fast-neutron irradiation and subcutaneously applied carbon tetrachloride or chloroform in C57Bl6 mice.
作者信息
Habs H, Künstler K, Schmähl D, Tomatis L
出版信息
Cancer Lett. 1983 Aug;20(1):13-20. doi: 10.1016/0304-3835(83)90181-7.
PMID:6362844
Abstract
Male and female C57Bl6 mice received a single whole-body dose of irradiation with 170 rad or 330 rad of fast neutrons. Nine weeks later they were given a single subcutaneous injection of carbon tetrachloride or chloroform. Chloroform did not influence the occurrence of tumours, but carbon tetrachloride markedly increased the incidence of radiation-induced liver carcinomas.
摘要
雄性和雌性C57Bl6小鼠接受了单次全身170拉德或330拉德快中子照射。九周后，它们被皮下注射了一次四氯化碳或氯仿。氯仿对肿瘤的发生没有影响，但四氯化碳显著增加了辐射诱导的肝癌发病率。
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